Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants

Kulawan Rojananuangnit, Nuttawan Sudjinda Glaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, Nakhon Pathom, ThailandCorrespondence: Kulawan RojananuangnitGlaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, 52 Moo 2 Rai Khing District, Samp...

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Autores principales:	Rojananuangnit K, Sudjinda N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	quality of life in glaucomatous patients utility index of glaucoma patient-reported outcome measures (proms) the visual function questionnaire utility index (vfq-ui) in glaucoma the european quality of life questionnaire (eq-5d-5l) in glaucoma the visual function questionnaire 28 thai-version (vfq-28) Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/0e47d0d1d78941c4b5914ab111cfe89c
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spelling	oai:doaj.org-article:0e47d0d1d78941c4b5914ab111cfe89c2021-12-02T16:22:18ZUtility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants1177-5483https://doaj.org/article/0e47d0d1d78941c4b5914ab111cfe89c2021-02-01T00:00:00Zhttps://www.dovepress.com/utility-index-and-patient-reported-outcome-measures-in-glaucomatous-pa-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Kulawan Rojananuangnit, Nuttawan Sudjinda Glaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, Nakhon Pathom, ThailandCorrespondence: Kulawan RojananuangnitGlaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, 52 Moo 2 Rai Khing District, Sampran, Nakhon Pathom, 73210, ThailandTel +66 34388712Fax +66 25897296Email kulawan@me.comPurpose: Utility index is a significant outcome in terms of health economics assessment while patient-reported outcome measure (PROMs) evaluates quality of life (QOL) from patient’s perspective. Our objective was to evaluate both utility indices and PROMs using generic and eye specific QOL in glaucomatous patients compared with normal population.Methods: This is a case-control study. We interviewed normal and glaucomatous participants with the European Quality of Life questionnaire (EQ-5D-5L), the European visual analogue scale (EQ-VAS) and the visual function questionnaire 28 (Thai version) (VFQ-28). The visual function questionnaire utility index (VFQ-UI) and generic utility index from EQ-5D-5L were calculated.Results: There were 47 normal and 127 glaucomatous participants in this study. Amongst glaucoma group, 35 participants were in the early stage of the disease, 43 were in the moderate stage, 30 normal vision participants were in the severe stage, 14 participants had blindness one eye, and 5 had blindness both eyes. The mean age of the participants in both groups was statistically similar (63.78± 6.84 vs 66.30± 8.93 years old, respectively, p=0.062). Underlying diseases between groups were also comparable. The EQ-5D-5L utility index score and the EQ-VAS score were not statistically different between normal and glaucomatous groups, respectively (EQ-5D-5L: 0.874± 0.122 vs 0.837± 0.191, p=0.215; EQ VAS: 76.06± 15.07 vs 74.02 ± 15.10, p=0.43). By contrast, VFQ-UI of the glaucomatous group was significantly lower than that of the normal group, (VFQ-UI: 0.833± 0.147 vs 0.895± 0.070, accordingly, p< 0.05).Conclusions: Utility index from the VFQ-UI was a relevant PROMs for evaluating the QOL of glaucomatous patients in terms of visual function specificity and acceptable validity.Keywords: quality of life in glaucomatous patients, utility index of glaucoma, patient-reported outcome measures, PROMs, the visual function questionnaire utility index in glaucoma, VFQ-UI, the European Quality of Life questionnaire in glaucoma, EQ-5D-5L, the visual function questionnaire 28 Thai-version, VFQ-28Rojananuangnit KSudjinda NDove Medical Pressarticlequality of life in glaucomatous patientsutility index of glaucomapatient-reported outcome measures (proms)the visual function questionnaire utility index (vfq-ui) in glaucomathe european quality of life questionnaire (eq-5d-5l) in glaucomathe visual function questionnaire 28 thai-version (vfq-28)OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 835-843 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	quality of life in glaucomatous patients utility index of glaucoma patient-reported outcome measures (proms) the visual function questionnaire utility index (vfq-ui) in glaucoma the european quality of life questionnaire (eq-5d-5l) in glaucoma the visual function questionnaire 28 thai-version (vfq-28) Ophthalmology RE1-994
spellingShingle	quality of life in glaucomatous patients utility index of glaucoma patient-reported outcome measures (proms) the visual function questionnaire utility index (vfq-ui) in glaucoma the european quality of life questionnaire (eq-5d-5l) in glaucoma the visual function questionnaire 28 thai-version (vfq-28) Ophthalmology RE1-994 Rojananuangnit K Sudjinda N Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
description	Kulawan Rojananuangnit, Nuttawan Sudjinda Glaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, Nakhon Pathom, ThailandCorrespondence: Kulawan RojananuangnitGlaucoma Unit, Ophthalmology Department, Mettapracharak (Wat Rai Khing) Hospital, 52 Moo 2 Rai Khing District, Sampran, Nakhon Pathom, 73210, ThailandTel +66 34388712Fax +66 25897296Email kulawan@me.comPurpose: Utility index is a significant outcome in terms of health economics assessment while patient-reported outcome measure (PROMs) evaluates quality of life (QOL) from patient’s perspective. Our objective was to evaluate both utility indices and PROMs using generic and eye specific QOL in glaucomatous patients compared with normal population.Methods: This is a case-control study. We interviewed normal and glaucomatous participants with the European Quality of Life questionnaire (EQ-5D-5L), the European visual analogue scale (EQ-VAS) and the visual function questionnaire 28 (Thai version) (VFQ-28). The visual function questionnaire utility index (VFQ-UI) and generic utility index from EQ-5D-5L were calculated.Results: There were 47 normal and 127 glaucomatous participants in this study. Amongst glaucoma group, 35 participants were in the early stage of the disease, 43 were in the moderate stage, 30 normal vision participants were in the severe stage, 14 participants had blindness one eye, and 5 had blindness both eyes. The mean age of the participants in both groups was statistically similar (63.78± 6.84 vs 66.30± 8.93 years old, respectively, p=0.062). Underlying diseases between groups were also comparable. The EQ-5D-5L utility index score and the EQ-VAS score were not statistically different between normal and glaucomatous groups, respectively (EQ-5D-5L: 0.874± 0.122 vs 0.837± 0.191, p=0.215; EQ VAS: 76.06± 15.07 vs 74.02 ± 15.10, p=0.43). By contrast, VFQ-UI of the glaucomatous group was significantly lower than that of the normal group, (VFQ-UI: 0.833± 0.147 vs 0.895± 0.070, accordingly, p< 0.05).Conclusions: Utility index from the VFQ-UI was a relevant PROMs for evaluating the QOL of glaucomatous patients in terms of visual function specificity and acceptable validity.Keywords: quality of life in glaucomatous patients, utility index of glaucoma, patient-reported outcome measures, PROMs, the visual function questionnaire utility index in glaucoma, VFQ-UI, the European Quality of Life questionnaire in glaucoma, EQ-5D-5L, the visual function questionnaire 28 Thai-version, VFQ-28
format	article
author	Rojananuangnit K Sudjinda N
author_facet	Rojananuangnit K Sudjinda N
author_sort	Rojananuangnit K
title	Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
title_short	Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
title_full	Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
title_fullStr	Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
title_full_unstemmed	Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants
title_sort	utility index and patient-reported outcome measures in glaucomatous patients comparing with normal participants
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/0e47d0d1d78941c4b5914ab111cfe89c
work_keys_str_mv	AT rojananuangnitk utilityindexandpatientreportedoutcomemeasuresinglaucomatouspatientscomparingwithnormalparticipants AT sudjindan utilityindexandpatientreportedoutcomemeasuresinglaucomatouspatientscomparingwithnormalparticipants
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Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants

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