A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.

We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK) chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK t...

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Bibliographic Details
Main Authors: Françoise Brignole-Baudouin, Nicolas Desbenoit, Gregory Hamm, Hong Liang, Jean-Pierre Both, Alain Brunelle, Isabelle Fournier, Vincent Guerineau, Raphael Legouffe, Jonathan Stauber, David Touboul, Maxence Wisztorski, Michel Salzet, Olivier Laprevote, Christophe Baudouin
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/0e48dab77fee420da2f8b75cb7178b4f
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https://doaj.org/article/0e48dab77fee420da2f8b75cb7178b4f

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