Chromosome arm aneuploidies shape tumour evolution and drug response

Chromosome arm aneuploidies shape tumour evolution and drug response

Chromosome arm-level aneuploidies (CAAs) are frequently observed in cancer. Here, the authors analyse CAA landscapes across different tumour types, relating these chromosome arm gains and losses to tumour evolution, metastasis, patient survival and response to a range of anti-cancer therapies.

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Detalles Bibliográficos
Autores principales: Ankit Shukla, Thu H. M. Nguyen, Sarat B. Moka, Jonathan J. Ellis, John P. Grady, Harald Oey, Alexandre S. Cristino, Kum Kum Khanna, Dirk P. Kroese, Lutz Krause, Eloise Dray, J. Lynn Fink, Pascal H. G. Duijf
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/0e49d0a39fa34863b24fe89eadb7f3d8
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