QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS

Abstract. This work was aimed for studying immunity markers, especially, T-regulatory cells, in patients suffering from polypous rhinosinusitis and treated with nasal steroids, in frame of integrated preventive treatment. The study included fifteen patients of both sexes (18 to 60 years of age), and...

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Autores principales: M. V. Semenov, A. V. Zurochka, V. A. Zurochka
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/0e4dad2fbfbf40f198051cd4bad22cfd
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spelling oai:doaj.org-article:0e4dad2fbfbf40f198051cd4bad22cfd2021-11-18T08:03:40ZQUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS1563-06252313-741X10.15789/1563-0625-2012-3-233-238https://doaj.org/article/0e4dad2fbfbf40f198051cd4bad22cfd2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/360https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. This work was aimed for studying immunity markers, especially, T-regulatory cells, in patients suffering from polypous rhinosinusitis and treated with nasal steroids, in frame of integrated preventive treatment. The study included fifteen patients of both sexes (18 to 60 years of age), and eighteen persons with difficulties of nasal breathing not associated with inflammatory events. T-regulatory cells were determined by a specific set of membrane receptors (CD4+, CD25+, CD127-). We have shown a significant reduction in T-regulatory cell contents prior to treatment, followed by their increase to normal levels in the course of therapy.M. V. SemenovA. V. ZurochkaV. A. ZurochkaSPb RAACIarticlepolypous rhinosinusitisflow cytometryt-regulatory cellstopical glucocorticoidsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 3, Pp 233-238 (2014)
institution DOAJ
collection DOAJ
language RU
topic polypous rhinosinusitis
flow cytometry
t-regulatory cells
topical glucocorticoids
Immunologic diseases. Allergy
RC581-607
spellingShingle polypous rhinosinusitis
flow cytometry
t-regulatory cells
topical glucocorticoids
Immunologic diseases. Allergy
RC581-607
M. V. Semenov
A. V. Zurochka
V. A. Zurochka
QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
description Abstract. This work was aimed for studying immunity markers, especially, T-regulatory cells, in patients suffering from polypous rhinosinusitis and treated with nasal steroids, in frame of integrated preventive treatment. The study included fifteen patients of both sexes (18 to 60 years of age), and eighteen persons with difficulties of nasal breathing not associated with inflammatory events. T-regulatory cells were determined by a specific set of membrane receptors (CD4+, CD25+, CD127-). We have shown a significant reduction in T-regulatory cell contents prior to treatment, followed by their increase to normal levels in the course of therapy.
format article
author M. V. Semenov
A. V. Zurochka
V. A. Zurochka
author_facet M. V. Semenov
A. V. Zurochka
V. A. Zurochka
author_sort M. V. Semenov
title QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
title_short QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
title_full QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
title_fullStr QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
title_full_unstemmed QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
title_sort quantititative changes of t-regulatory cells in patients with polipous rhinosinusitis treated by nasal glucocorticosteroids
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/0e4dad2fbfbf40f198051cd4bad22cfd
work_keys_str_mv AT mvsemenov quantititativechangesoftregulatorycellsinpatientswithpolipousrhinosinusitistreatedbynasalglucocorticosteroids
AT avzurochka quantititativechangesoftregulatorycellsinpatientswithpolipousrhinosinusitistreatedbynasalglucocorticosteroids
AT vazurochka quantititativechangesoftregulatorycellsinpatientswithpolipousrhinosinusitistreatedbynasalglucocorticosteroids
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