Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery

Abstract Health care-related infections are frequent and among them surgical site infection (SSI) are the most frequent in hospitals. The objective was to evaluate the adequacy of antibiotic prophylaxis in patients undergoing neck surgery and its relationship with the incidence of surgical site infe...

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Autores principales: M. Alonso-García, A. Toledano-Muñoz, J. M. Aparicio-Fernández, F. M. De-la-Rosa-Astacio, D. Rodríguez-Villar, A. Gil-de-Miguel, M. Durán-Poveda, G. Rodríguez-Caravaca
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0e4fc92b5a3941828d7490ee320e786d
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spelling oai:doaj.org-article:0e4fc92b5a3941828d7490ee320e786d2021-12-02T15:07:47ZAdequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery10.1038/s41598-021-95831-92045-2322https://doaj.org/article/0e4fc92b5a3941828d7490ee320e786d2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95831-9https://doaj.org/toc/2045-2322Abstract Health care-related infections are frequent and among them surgical site infection (SSI) are the most frequent in hospitals. The objective was to evaluate the adequacy of antibiotic prophylaxis in patients undergoing neck surgery and its relationship with the incidence of surgical site infection (SSI). Prospective cohort study. The adequacy of antibiotic prophylaxis in patients undergoing neck surgery was evaluated. Antibiotic prophylaxis was considered adequate when it conformed to all items of the protocol (antibiotic used, time of administration, administration route, dose and duration). The cumulative incidence of SSI was calculated, and the relationship between SSI and antibiotic prophylaxis adequacy was determined using adjusted relative risk (RR). Antibiotic prophylaxis was administered in 63 patients and was adequate in 85.7% (95% CI 75.0–92.3) of them. The cumulative incidence of SSI was 6.4% (95% CI 3.4–11.8). There was no significant relationship between antibiotic prophylaxis inadequacy and the incidence of SSI (RR = 2.4, 95% CI 0.6–10.6). Adequacy of antibiotic prophylaxis was high and it did not affect the incidence of SSIs.M. Alonso-GarcíaA. Toledano-MuñozJ. M. Aparicio-FernándezF. M. De-la-Rosa-AstacioD. Rodríguez-VillarA. Gil-de-MiguelM. Durán-PovedaG. Rodríguez-CaravacaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
M. Alonso-García
A. Toledano-Muñoz
J. M. Aparicio-Fernández
F. M. De-la-Rosa-Astacio
D. Rodríguez-Villar
A. Gil-de-Miguel
M. Durán-Poveda
G. Rodríguez-Caravaca
Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
description Abstract Health care-related infections are frequent and among them surgical site infection (SSI) are the most frequent in hospitals. The objective was to evaluate the adequacy of antibiotic prophylaxis in patients undergoing neck surgery and its relationship with the incidence of surgical site infection (SSI). Prospective cohort study. The adequacy of antibiotic prophylaxis in patients undergoing neck surgery was evaluated. Antibiotic prophylaxis was considered adequate when it conformed to all items of the protocol (antibiotic used, time of administration, administration route, dose and duration). The cumulative incidence of SSI was calculated, and the relationship between SSI and antibiotic prophylaxis adequacy was determined using adjusted relative risk (RR). Antibiotic prophylaxis was administered in 63 patients and was adequate in 85.7% (95% CI 75.0–92.3) of them. The cumulative incidence of SSI was 6.4% (95% CI 3.4–11.8). There was no significant relationship between antibiotic prophylaxis inadequacy and the incidence of SSI (RR = 2.4, 95% CI 0.6–10.6). Adequacy of antibiotic prophylaxis was high and it did not affect the incidence of SSIs.
format article
author M. Alonso-García
A. Toledano-Muñoz
J. M. Aparicio-Fernández
F. M. De-la-Rosa-Astacio
D. Rodríguez-Villar
A. Gil-de-Miguel
M. Durán-Poveda
G. Rodríguez-Caravaca
author_facet M. Alonso-García
A. Toledano-Muñoz
J. M. Aparicio-Fernández
F. M. De-la-Rosa-Astacio
D. Rodríguez-Villar
A. Gil-de-Miguel
M. Durán-Poveda
G. Rodríguez-Caravaca
author_sort M. Alonso-García
title Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
title_short Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
title_full Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
title_fullStr Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
title_full_unstemmed Adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
title_sort adequacy of antibiotic prophylaxis and incidence of surgical site infections in neck surgery
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0e4fc92b5a3941828d7490ee320e786d
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