Proteasome Inhibitors and Their Pharmacokinetics, Pharmacodynamics, and Metabolism
The proteasome is responsible for mediating intracellular protein degradation and regulating cellular function with impact on tumor and immune effector cell biology. The proteasome is found predominantly in two forms, the constitutive proteasome and the immunoproteasome. It has been validated as a t...
Guardado en:
Autores principales: | Jinhai Wang, Ying Fang, R. Andrea Fan, Christopher J. Kirk |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0e5977f856364f8c9a66879a821db2e7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A Cell-Based Platform for the Investigation of Immunoproteasome Subunit β5i Expression and Biology of β5i-Containing Proteasomes
por: Alexander Burov, et al.
Publicado: (2021) -
High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors
por: Lenka Besse, et al.
Publicado: (2021) -
DESIGN, ADMET AND DOCKING STUDIES ON SOME NOVEL CHALCONE DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE ENZYME INHIBITORS
por: ASOKKUMAR,KUPPUSAMY, et al.
Publicado: (2012) -
On the Role of the Immunoproteasome in Protein Homeostasis
por: Michael Basler, et al.
Publicado: (2021) -
Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction
por: Saivageethi Nuthikattu, et al.
Publicado: (2021)