Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells

Abstract HIV prevention research is focused on combining antiretrovirals (ARV) and progestin contraceptives to prevent HIV infection and pregnancy. The possibility that progestins compromise ARV anti-HIV activity prompted us to evaluate the effects of progestins on tenofovir (TFV) and TFV-alafenamid...

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Auteurs principaux: Zheng Shen, Marta Rodriguez-Garcia, Mickey V. Patel, Jack Bodwell, Angela D. M. Kashuba, Charles R. Wira
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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R
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Accès en ligne:https://doaj.org/article/0e63fdb8ac994dd2924569421206fb6e
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