A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

Abstract The interactions of fibroblast-like synoviocyte (FLS)-derived pro-inflammatory cytokines/chemokines and immune cells support the recruitment and activation of inflammatory cells in RA. Here, we show for the first time that the classical myokine myostatin (GDF-8) is involved in the recruitme...

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Autores principales: Michelle Fennen, Toni Weinhage, Vanessa Kracke, Johanna Intemann, Georg Varga, Corinna Wehmeyer, Dirk Foell, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0e68a05c59a446c9abd58a77cfaf8633
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