ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

Mitochondrial DNA is found in nucleoids, which are distributed throughout the mitochondrial network and are thought to be passively distributed. Here, the authors show that mitochondrial dynamic tubulation at ER-mitochondria contact sites actively transports nucleoids.

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Autores principales:	Jinshan Qin, Yuting Guo, Boxin Xue, Peng Shi, Yang Chen, Qian Peter Su, Huiwen Hao, Shujuan Zhao, Congying Wu, Li Yu, Dong Li, Yujie Sun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e68e3af662c40148c8dad39f719f91d
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spelling	oai:doaj.org-article:0e68e3af662c40148c8dad39f719f91d2021-12-02T19:12:26ZER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation10.1038/s41467-020-18202-42041-1723https://doaj.org/article/0e68e3af662c40148c8dad39f719f91d2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18202-4https://doaj.org/toc/2041-1723Mitochondrial DNA is found in nucleoids, which are distributed throughout the mitochondrial network and are thought to be passively distributed. Here, the authors show that mitochondrial dynamic tubulation at ER-mitochondria contact sites actively transports nucleoids.Jinshan QinYuting GuoBoxin XuePeng ShiYang ChenQian Peter SuHuiwen HaoShujuan ZhaoCongying WuLi YuDong LiYujie SunNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jinshan Qin Yuting Guo Boxin Xue Peng Shi Yang Chen Qian Peter Su Huiwen Hao Shujuan Zhao Congying Wu Li Yu Dong Li Yujie Sun ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
description	Mitochondrial DNA is found in nucleoids, which are distributed throughout the mitochondrial network and are thought to be passively distributed. Here, the authors show that mitochondrial dynamic tubulation at ER-mitochondria contact sites actively transports nucleoids.
format	article
author	Jinshan Qin Yuting Guo Boxin Xue Peng Shi Yang Chen Qian Peter Su Huiwen Hao Shujuan Zhao Congying Wu Li Yu Dong Li Yujie Sun
author_facet	Jinshan Qin Yuting Guo Boxin Xue Peng Shi Yang Chen Qian Peter Su Huiwen Hao Shujuan Zhao Congying Wu Li Yu Dong Li Yujie Sun
author_sort	Jinshan Qin
title	ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
title_short	ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
title_full	ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
title_fullStr	ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
title_full_unstemmed	ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation
title_sort	er-mitochondria contacts promote mtdna nucleoids active transportation via mitochondrial dynamic tubulation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0e68e3af662c40148c8dad39f719f91d
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ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

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