Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor

Abstract The purpose of the study was to investigate the application of virtual monoenergetic images (VMIs) in reducing metal artifacts in rabbit VX2 liver cancer models treated with microwave ablation (MWA) therapy. A total of 31 VX2 liver cancer models that accepted CT-guided percutaneous microwav...

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Autores principales:	Guorong Wang, Qinzong Gao, Zhiwei Wang, Xiaomei Lu, Shenghui Yu, Zhengyu Jin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0e6a39baa8a34e5e9201950a90ee7f0b
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spelling	oai:doaj.org-article:0e6a39baa8a34e5e9201950a90ee7f0b2021-12-02T13:41:00ZReduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor10.1038/s41598-021-88853-w2045-2322https://doaj.org/article/0e6a39baa8a34e5e9201950a90ee7f0b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88853-whttps://doaj.org/toc/2045-2322Abstract The purpose of the study was to investigate the application of virtual monoenergetic images (VMIs) in reducing metal artifacts in rabbit VX2 liver cancer models treated with microwave ablation (MWA) therapy. A total of 31 VX2 liver cancer models that accepted CT-guided percutaneous microwave ablation were analyzed. Conventional images (CIs) with the most severe metallic artifacts and their corresponding energy levels from 40 to 200 keV with 10 keV increment of VMIs were reconstructed for further analysis. Objective image analysis was assessed by recording the attenuation (HU) and standard deviation of the most severe hyper/hypodense artifacts as well as artifact-impaired liver parenchyma tissue. Two radiologists visually evaluated the extent of artifact reduction, assessed data obtained by a diagnostic evaluation of liver tissues, and appraised the appearance of new artifacts according to the grade score. Statistical analysis was performed to compare the difference between CIs and each energy level of VMIs. For subjective assessment, reductions in hyperdense and hypodense artifacts were observed at 170–200 keV and 160–200 keV, respectively. The outcomes of the diagnostic evaluation of adjacent liver tissue were statistically higher at 140–200 keV for VMIs than for CIs. In terms of objective evaluation results, VMIs at 90–200 keV reduced the corrected attenuation of hyperdense and of artifact-impaired liver parenchyma compared with CIs (P < 0.001). When VMIs at 80–200 keV decreased the hypodense artifacts (P < 0.001). Therefore, we concluded that VMIs at 170–200 keV can obviously decrease the microwave ablation needle-related metal artifacts objectively and subjectively in rabbit VX2 liver cancer models.Guorong WangQinzong GaoZhiwei WangXiaomei LuShenghui YuZhengyu JinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Guorong Wang Qinzong Gao Zhiwei Wang Xiaomei Lu Shenghui Yu Zhengyu Jin Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
description	Abstract The purpose of the study was to investigate the application of virtual monoenergetic images (VMIs) in reducing metal artifacts in rabbit VX2 liver cancer models treated with microwave ablation (MWA) therapy. A total of 31 VX2 liver cancer models that accepted CT-guided percutaneous microwave ablation were analyzed. Conventional images (CIs) with the most severe metallic artifacts and their corresponding energy levels from 40 to 200 keV with 10 keV increment of VMIs were reconstructed for further analysis. Objective image analysis was assessed by recording the attenuation (HU) and standard deviation of the most severe hyper/hypodense artifacts as well as artifact-impaired liver parenchyma tissue. Two radiologists visually evaluated the extent of artifact reduction, assessed data obtained by a diagnostic evaluation of liver tissues, and appraised the appearance of new artifacts according to the grade score. Statistical analysis was performed to compare the difference between CIs and each energy level of VMIs. For subjective assessment, reductions in hyperdense and hypodense artifacts were observed at 170–200 keV and 160–200 keV, respectively. The outcomes of the diagnostic evaluation of adjacent liver tissue were statistically higher at 140–200 keV for VMIs than for CIs. In terms of objective evaluation results, VMIs at 90–200 keV reduced the corrected attenuation of hyperdense and of artifact-impaired liver parenchyma compared with CIs (P < 0.001). When VMIs at 80–200 keV decreased the hypodense artifacts (P < 0.001). Therefore, we concluded that VMIs at 170–200 keV can obviously decrease the microwave ablation needle-related metal artifacts objectively and subjectively in rabbit VX2 liver cancer models.
format	article
author	Guorong Wang Qinzong Gao Zhiwei Wang Xiaomei Lu Shenghui Yu Zhengyu Jin
author_facet	Guorong Wang Qinzong Gao Zhiwei Wang Xiaomei Lu Shenghui Yu Zhengyu Jin
author_sort	Guorong Wang
title	Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
title_short	Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
title_full	Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
title_fullStr	Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
title_full_unstemmed	Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor
title_sort	reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral ct in a rabbit model with vx2 tumor
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0e6a39baa8a34e5e9201950a90ee7f0b
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Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor

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