Mastalgia in infertility: search for additional possibilities of therapy

Aim. To assess the efficacy and safety of using the homeopathic drug Mastopol for the relief of mastalgia in women with infertility, including those associated with endometriosis, as well as to study the drug tolerability and adherence to the treatment, as well as to determine its antiproliferative...

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Autores principales:	Ksenia V. Krasnopolskaya, Vera E. Balan, Irina Y. Ershova, Elena O. Skorik, Sergey E. Malygin, Mekan R. Orazov, Lilia R. Toktar, Elena V. Lagutina
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	mastalgia infertility mastopol Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/0e6c1354f5a14999ae7fc97c0ec91a9c
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spelling	oai:doaj.org-article:0e6c1354f5a14999ae7fc97c0ec91a9c2021-12-02T19:22:24ZMastalgia in infertility: search for additional possibilities of therapy2079-56962079-583110.26442/20795696.2021.4.201084https://doaj.org/article/0e6c1354f5a14999ae7fc97c0ec91a9c2021-09-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/80424/60966https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831Aim. To assess the efficacy and safety of using the homeopathic drug Mastopol for the relief of mastalgia in women with infertility, including those associated with endometriosis, as well as to study the drug tolerability and adherence to the treatment, as well as to determine its antiproliferative and analgesic effects in patients of the study cohort. Study design: open-label, randomized, non-comparative, observational study. Material and methods. 79 infertile women with mastalgia (67 with cyclic mastalgia and 12 with acyclic mastalgia) were examined and treated with Mastopol. Mastopol was prescribed 1 tablet 3 times a day sublingually. The course of treatment was 8 weeks. The efficacy of mastalgia relief was assessed using a Visual Analogue Scale (VAS). Treatment outcomes were considered good if pain severity by the VAS decreased by 4 or more points from the baseline levels at the end of Mastopol treatment course. Results. One Mastopol treatment course provided good treatment outcomes in 76,2% of patients with cyclic mastalgia and in 33,3% of patients with acyclic mastalgia. There were no adverse reactions or complications in patients treated with Mastopol. Conclusions. Mastopol has established itself as a quite effective and safe drug in patients of the study cohort; if there is an insufficient effect, Mastopol can supplement traditional pharmacological agents recorded in the current clinical guidelines.Ksenia V. KrasnopolskayaVera E. BalanIrina Y. ErshovaElena O. SkorikSergey E. MalyginMekan R. OrazovLilia R. ToktarElena V. LagutinaIP Berlin A.V. articlemastalgiainfertilitymastopolGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 4, Pp 354-363 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	mastalgia infertility mastopol Gynecology and obstetrics RG1-991
spellingShingle	mastalgia infertility mastopol Gynecology and obstetrics RG1-991 Ksenia V. Krasnopolskaya Vera E. Balan Irina Y. Ershova Elena O. Skorik Sergey E. Malygin Mekan R. Orazov Lilia R. Toktar Elena V. Lagutina Mastalgia in infertility: search for additional possibilities of therapy
description	Aim. To assess the efficacy and safety of using the homeopathic drug Mastopol for the relief of mastalgia in women with infertility, including those associated with endometriosis, as well as to study the drug tolerability and adherence to the treatment, as well as to determine its antiproliferative and analgesic effects in patients of the study cohort. Study design: open-label, randomized, non-comparative, observational study. Material and methods. 79 infertile women with mastalgia (67 with cyclic mastalgia and 12 with acyclic mastalgia) were examined and treated with Mastopol. Mastopol was prescribed 1 tablet 3 times a day sublingually. The course of treatment was 8 weeks. The efficacy of mastalgia relief was assessed using a Visual Analogue Scale (VAS). Treatment outcomes were considered good if pain severity by the VAS decreased by 4 or more points from the baseline levels at the end of Mastopol treatment course. Results. One Mastopol treatment course provided good treatment outcomes in 76,2% of patients with cyclic mastalgia and in 33,3% of patients with acyclic mastalgia. There were no adverse reactions or complications in patients treated with Mastopol. Conclusions. Mastopol has established itself as a quite effective and safe drug in patients of the study cohort; if there is an insufficient effect, Mastopol can supplement traditional pharmacological agents recorded in the current clinical guidelines.
format	article
author	Ksenia V. Krasnopolskaya Vera E. Balan Irina Y. Ershova Elena O. Skorik Sergey E. Malygin Mekan R. Orazov Lilia R. Toktar Elena V. Lagutina
author_facet	Ksenia V. Krasnopolskaya Vera E. Balan Irina Y. Ershova Elena O. Skorik Sergey E. Malygin Mekan R. Orazov Lilia R. Toktar Elena V. Lagutina
author_sort	Ksenia V. Krasnopolskaya
title	Mastalgia in infertility: search for additional possibilities of therapy
title_short	Mastalgia in infertility: search for additional possibilities of therapy
title_full	Mastalgia in infertility: search for additional possibilities of therapy
title_fullStr	Mastalgia in infertility: search for additional possibilities of therapy
title_full_unstemmed	Mastalgia in infertility: search for additional possibilities of therapy
title_sort	mastalgia in infertility: search for additional possibilities of therapy
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/0e6c1354f5a14999ae7fc97c0ec91a9c
work_keys_str_mv	AT kseniavkrasnopolskaya mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT veraebalan mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT irinayershova mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT elenaoskorik mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT sergeyemalygin mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT mekanrorazov mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT liliartoktar mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy AT elenavlagutina mastalgiaininfertilitysearchforadditionalpossibilitiesoftherapy
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Mastalgia in infertility: search for additional possibilities of therapy

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