Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis.

<h4>Background</h4>The ten mouse and six human members of the Schlafen (Slfn) gene family all contain an AAA domain. Little is known of their function, but previous studies suggest roles in immune cell development. In this report, we assessed Slfn regulation and function in macrophages,...

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Autores principales: Wendy J van Zuylen, Valerie Garceau, Adi Idris, Kate Schroder, Katharine M Irvine, Jane E Lattin, Dmitry A Ovchinnikov, Andrew C Perkins, Andrew D Cook, John A Hamilton, Paul J Hertzog, Katryn J Stacey, Stuart Kellie, David A Hume, Matthew J Sweet
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0e772b52cc8148969f6d70d48c2a29ad
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