Anti-phage islands force their target phage to directly mediate island excision and spread

Mobile genetic elements called PLEs protect Vibrio cholerae from infection with phage ICP1 by unclear mechanisms. Here, McKitterick and Seed show that a PLE-encoded large serine recombinase exploits an ICP1 protein as a recombination directionality factor to excise this PLE in response to phage infe...

Full description

Saved in:
Bibliographic Details
Main Authors: Amelia C. McKitterick, Kimberley D. Seed
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/0e797a9c4ba3467e9bd2c5ec57184a1f
Tags: Add Tag
No Tags, Be the first to tag this record!