Blood genome expression profiles in infants with congenital cytomegalovirus infection

Congenital CMV infection can result in sensorineural hearing loss, but predicting this outcome is not yet possible. Here, the authors show that while blood gene expression profiles are not substantially different between symptomatic and asymptomatic infants with congenital CMV infection, a 16-gene s...

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Autores principales:	Christopher P. Ouellette, Pablo J. Sánchez, Zhaohui Xu, Derek Blankenship, Fiker Zeray, Andrea Ronchi, Masako Shimamura, Damien Chaussabel, Lizette Lee, Kris E. Owen, Angela G. Shoup, Octavio Ramilo, Asuncion Mejias
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e7bd5967cd34f6e9578ccd9a6bf97f7
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spelling	oai:doaj.org-article:0e7bd5967cd34f6e9578ccd9a6bf97f72021-12-02T18:37:05ZBlood genome expression profiles in infants with congenital cytomegalovirus infection10.1038/s41467-020-17178-52041-1723https://doaj.org/article/0e7bd5967cd34f6e9578ccd9a6bf97f72020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17178-5https://doaj.org/toc/2041-1723Congenital CMV infection can result in sensorineural hearing loss, but predicting this outcome is not yet possible. Here, the authors show that while blood gene expression profiles are not substantially different between symptomatic and asymptomatic infants with congenital CMV infection, a 16-gene signature is identified and able to predict late-onset hearing loss in these children.Christopher P. OuellettePablo J. SánchezZhaohui XuDerek BlankenshipFiker ZerayAndrea RonchiMasako ShimamuraDamien ChaussabelLizette LeeKris E. OwenAngela G. ShoupOctavio RamiloAsuncion MejiasNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher P. Ouellette Pablo J. Sánchez Zhaohui Xu Derek Blankenship Fiker Zeray Andrea Ronchi Masako Shimamura Damien Chaussabel Lizette Lee Kris E. Owen Angela G. Shoup Octavio Ramilo Asuncion Mejias Blood genome expression profiles in infants with congenital cytomegalovirus infection
description	Congenital CMV infection can result in sensorineural hearing loss, but predicting this outcome is not yet possible. Here, the authors show that while blood gene expression profiles are not substantially different between symptomatic and asymptomatic infants with congenital CMV infection, a 16-gene signature is identified and able to predict late-onset hearing loss in these children.
format	article
author	Christopher P. Ouellette Pablo J. Sánchez Zhaohui Xu Derek Blankenship Fiker Zeray Andrea Ronchi Masako Shimamura Damien Chaussabel Lizette Lee Kris E. Owen Angela G. Shoup Octavio Ramilo Asuncion Mejias
author_facet	Christopher P. Ouellette Pablo J. Sánchez Zhaohui Xu Derek Blankenship Fiker Zeray Andrea Ronchi Masako Shimamura Damien Chaussabel Lizette Lee Kris E. Owen Angela G. Shoup Octavio Ramilo Asuncion Mejias
author_sort	Christopher P. Ouellette
title	Blood genome expression profiles in infants with congenital cytomegalovirus infection
title_short	Blood genome expression profiles in infants with congenital cytomegalovirus infection
title_full	Blood genome expression profiles in infants with congenital cytomegalovirus infection
title_fullStr	Blood genome expression profiles in infants with congenital cytomegalovirus infection
title_full_unstemmed	Blood genome expression profiles in infants with congenital cytomegalovirus infection
title_sort	blood genome expression profiles in infants with congenital cytomegalovirus infection
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0e7bd5967cd34f6e9578ccd9a6bf97f7
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_version_	1718377843060113408

Blood genome expression profiles in infants with congenital cytomegalovirus infection

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