Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen

Stool biomarkers hold promise for monitoring disease activity and predicting clinical course in inflammatory bowel disease (IBD) as they originate from the inflamed tissue. Here the authors report an aptamer-based proteomic screen, and discover several stool proteins that predict remission at four w...

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Autores principales: Sanam Soomro, Suresh Venkateswaran, Kamala Vanarsa, Marwa Kharboutli, Malavika Nidhi, Ramya Susarla, Ting Zhang, Prashanth Sasidharan, Kyung Hyun Lee, Joel Rosh, James Markowitz, Claudia Pedroza, Lee A. Denson, Jeffrey Hyams, Subra Kugathasan, Chandra Mohan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0e861c5d16cb448f88bdd0f9eeed0169
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spelling oai:doaj.org-article:0e861c5d16cb448f88bdd0f9eeed01692021-12-02T18:18:35ZPredicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen10.1038/s41467-021-24235-02041-1723https://doaj.org/article/0e861c5d16cb448f88bdd0f9eeed01692021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24235-0https://doaj.org/toc/2041-1723Stool biomarkers hold promise for monitoring disease activity and predicting clinical course in inflammatory bowel disease (IBD) as they originate from the inflamed tissue. Here the authors report an aptamer-based proteomic screen, and discover several stool proteins that predict remission at four weeks.Sanam SoomroSuresh VenkateswaranKamala VanarsaMarwa KharboutliMalavika NidhiRamya SusarlaTing ZhangPrashanth SasidharanKyung Hyun LeeJoel RoshJames MarkowitzClaudia PedrozaLee A. DensonJeffrey HyamsSubra KugathasanChandra MohanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sanam Soomro
Suresh Venkateswaran
Kamala Vanarsa
Marwa Kharboutli
Malavika Nidhi
Ramya Susarla
Ting Zhang
Prashanth Sasidharan
Kyung Hyun Lee
Joel Rosh
James Markowitz
Claudia Pedroza
Lee A. Denson
Jeffrey Hyams
Subra Kugathasan
Chandra Mohan
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
description Stool biomarkers hold promise for monitoring disease activity and predicting clinical course in inflammatory bowel disease (IBD) as they originate from the inflamed tissue. Here the authors report an aptamer-based proteomic screen, and discover several stool proteins that predict remission at four weeks.
format article
author Sanam Soomro
Suresh Venkateswaran
Kamala Vanarsa
Marwa Kharboutli
Malavika Nidhi
Ramya Susarla
Ting Zhang
Prashanth Sasidharan
Kyung Hyun Lee
Joel Rosh
James Markowitz
Claudia Pedroza
Lee A. Denson
Jeffrey Hyams
Subra Kugathasan
Chandra Mohan
author_facet Sanam Soomro
Suresh Venkateswaran
Kamala Vanarsa
Marwa Kharboutli
Malavika Nidhi
Ramya Susarla
Ting Zhang
Prashanth Sasidharan
Kyung Hyun Lee
Joel Rosh
James Markowitz
Claudia Pedroza
Lee A. Denson
Jeffrey Hyams
Subra Kugathasan
Chandra Mohan
author_sort Sanam Soomro
title Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
title_short Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
title_full Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
title_fullStr Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
title_full_unstemmed Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
title_sort predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0e861c5d16cb448f88bdd0f9eeed0169
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