TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons

TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons

Abstract Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing pathological pain experiences in tissue...

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Autores principales: Tianci Li, Gaoge Wang, Vivian Chin Chin Hui, Daniel Saad, Joao de Sousa Valente, Paolo La Montanara, Istvan Nagy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/0e8c624f13d84d4995ac9e642247fd89
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