Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction
Spontaneous coronary artery dissection (SCAD) is a cause of myocardial infarction Here, the authors present a genome-wide association study of SCAD, finding an association at 1q21.2 which potentially affects expression of ADAMTSL4.
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Nature Portfolio
2020
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oai:doaj.org-article:0e8dfd7e59bd450fafe736aa1d5dabf92021-12-02T16:38:27ZChromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction10.1038/s41467-020-17558-x2041-1723https://doaj.org/article/0e8dfd7e59bd450fafe736aa1d5dabf92020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17558-xhttps://doaj.org/toc/2041-1723Spontaneous coronary artery dissection (SCAD) is a cause of myocardial infarction Here, the authors present a genome-wide association study of SCAD, finding an association at 1q21.2 which potentially affects expression of ADAMTSL4.Jacqueline SawMin-Lee YangMark TrinderCatherine TcheandjieuChang XuAndrew StarovoytovIsabelle BirtMichael R. MathisKristina L. HunkerEllen M. SchmidtLinda JacksonNatalia Fendrikova-MahlayMatthew ZawistowskiChad M. BrummettSebastian ZoellnerAlexander KatzDawn M. ColemanKirby SwanChristopher J. O’DonnellMillion Veteran ProgramXiang ZhouJun Z. LiHeather L. GornikThemistocles L. AssimesJames C. StanleyLiam R. BrunhamSanthi K. GaneshNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jacqueline Saw Min-Lee Yang Mark Trinder Catherine Tcheandjieu Chang Xu Andrew Starovoytov Isabelle Birt Michael R. Mathis Kristina L. Hunker Ellen M. Schmidt Linda Jackson Natalia Fendrikova-Mahlay Matthew Zawistowski Chad M. Brummett Sebastian Zoellner Alexander Katz Dawn M. Coleman Kirby Swan Christopher J. O’Donnell Million Veteran Program Xiang Zhou Jun Z. Li Heather L. Gornik Themistocles L. Assimes James C. Stanley Liam R. Brunham Santhi K. Ganesh Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| description |
Spontaneous coronary artery dissection (SCAD) is a cause of myocardial infarction Here, the authors present a genome-wide association study of SCAD, finding an association at 1q21.2 which potentially affects expression of ADAMTSL4. |
| format |
article |
| author |
Jacqueline Saw Min-Lee Yang Mark Trinder Catherine Tcheandjieu Chang Xu Andrew Starovoytov Isabelle Birt Michael R. Mathis Kristina L. Hunker Ellen M. Schmidt Linda Jackson Natalia Fendrikova-Mahlay Matthew Zawistowski Chad M. Brummett Sebastian Zoellner Alexander Katz Dawn M. Coleman Kirby Swan Christopher J. O’Donnell Million Veteran Program Xiang Zhou Jun Z. Li Heather L. Gornik Themistocles L. Assimes James C. Stanley Liam R. Brunham Santhi K. Ganesh |
| author_facet |
Jacqueline Saw Min-Lee Yang Mark Trinder Catherine Tcheandjieu Chang Xu Andrew Starovoytov Isabelle Birt Michael R. Mathis Kristina L. Hunker Ellen M. Schmidt Linda Jackson Natalia Fendrikova-Mahlay Matthew Zawistowski Chad M. Brummett Sebastian Zoellner Alexander Katz Dawn M. Coleman Kirby Swan Christopher J. O’Donnell Million Veteran Program Xiang Zhou Jun Z. Li Heather L. Gornik Themistocles L. Assimes James C. Stanley Liam R. Brunham Santhi K. Ganesh |
| author_sort |
Jacqueline Saw |
| title |
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| title_short |
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| title_full |
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| title_fullStr |
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| title_full_unstemmed |
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| title_sort |
chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/0e8dfd7e59bd450fafe736aa1d5dabf9 |
| work_keys_str_mv |
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1718383556695162880 |