Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate

Abstract In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify non-antibiotic substances with broad-spectrum activity able to destroy the EPS matrix and enhance the effect of ant...

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Autores principales: JingJing Liu, Jean-Yves Madec, Alain Bousquet-Mélou, Marisa Haenni, Aude A. Ferran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0e8f2adad2b543d2a92fbf12f10b482b
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