Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis

Objective: This study aimed to make use of real-world medical records to explore the clinical characteristics, treatments, and outcomes of infantile hemangiomas in southeastern China. Methods: This study applied a retrospective observational method using real-world data derived from the electronic m...

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Autores principales:	Yantao Cai, Ying Ge, Carolina Oi Lam Ung, Fuli Li, Jiaqi Wang, Chenglai Xia, Hao Hu
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/0e95926536c74dccb4eec68ffbb15377
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spelling	oai:doaj.org-article:0e95926536c74dccb4eec68ffbb153772021-12-01T23:35:40ZTreatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis2050-312110.1177/20503121211056844https://doaj.org/article/0e95926536c74dccb4eec68ffbb153772021-11-01T00:00:00Zhttps://doi.org/10.1177/20503121211056844https://doaj.org/toc/2050-3121Objective: This study aimed to make use of real-world medical records to explore the clinical characteristics, treatments, and outcomes of infantile hemangiomas in southeastern China. Methods: This study applied a retrospective observational method using real-world data derived from the electronic medical records of the Foshan Women and Children Hospital, southeastern China dated between June 2014 and June 2019. Results: A total of 2427 patients with infantile hemangiomas were recruited in this study, including 942 (38.8%) males and 1485 (61.2%) females. Among the participants, 620 (25.5%) were high-risk infantile hemangioma, 449 (18.5%) were medium risk, and 1358 (56.0%) were low risk. A total of 14 treatment patterns in clinical practice were identified. The top 3 treatment patterns in each group of risk levels were the same: laser therapy, a combination of laser therapy and topical timolol maleate, and topical timolol maleate. The outcomes of the top 3 treatment patterns were significantly ( P < 0.05) different in each risk group. Conclusion: Among the top 3 treatment patterns, laser therapy or a combination of laser therapy and topical timolol maleate were more likely to have an “Excellent” outcome.Yantao CaiYing GeCarolina Oi Lam UngFuli LiJiaqi WangChenglai XiaHao HuSAGE PublishingarticleMedicine (General)R5-920ENSAGE Open Medicine, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Yantao Cai Ying Ge Carolina Oi Lam Ung Fuli Li Jiaqi Wang Chenglai Xia Hao Hu Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
description	Objective: This study aimed to make use of real-world medical records to explore the clinical characteristics, treatments, and outcomes of infantile hemangiomas in southeastern China. Methods: This study applied a retrospective observational method using real-world data derived from the electronic medical records of the Foshan Women and Children Hospital, southeastern China dated between June 2014 and June 2019. Results: A total of 2427 patients with infantile hemangiomas were recruited in this study, including 942 (38.8%) males and 1485 (61.2%) females. Among the participants, 620 (25.5%) were high-risk infantile hemangioma, 449 (18.5%) were medium risk, and 1358 (56.0%) were low risk. A total of 14 treatment patterns in clinical practice were identified. The top 3 treatment patterns in each group of risk levels were the same: laser therapy, a combination of laser therapy and topical timolol maleate, and topical timolol maleate. The outcomes of the top 3 treatment patterns were significantly ( P < 0.05) different in each risk group. Conclusion: Among the top 3 treatment patterns, laser therapy or a combination of laser therapy and topical timolol maleate were more likely to have an “Excellent” outcome.
format	article
author	Yantao Cai Ying Ge Carolina Oi Lam Ung Fuli Li Jiaqi Wang Chenglai Xia Hao Hu
author_facet	Yantao Cai Ying Ge Carolina Oi Lam Ung Fuli Li Jiaqi Wang Chenglai Xia Hao Hu
author_sort	Yantao Cai
title	Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
title_short	Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
title_full	Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
title_fullStr	Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
title_full_unstemmed	Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis
title_sort	treatment patterns and outcomes in children with infantile hemangiomas: a retrospective observational analysis
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/0e95926536c74dccb4eec68ffbb15377
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_version_	1718403967028822016

Treatment patterns and outcomes in children with infantile hemangiomas: A retrospective observational analysis

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