Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the pathways required for DNA repair in this organism.

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Autores principales:	Katy Poncin, Agnès Roba, Ravikumar Jimmidi, Georges Potemberg, Antonella Fioravanti, Nayla Francis, Kévin Willemart, Nicolas Zeippen, Arnaud Machelart, Emanuele G. Biondi, Eric Muraille, Stéphane P. Vincent, Xavier De Bolle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac
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spelling	oai:doaj.org-article:0e9cb03fdb914652b78daf4b8a72caac2021-12-02T14:39:17ZOccurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus10.1038/s41467-019-12516-82041-1723https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12516-8https://doaj.org/toc/2041-1723It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the pathways required for DNA repair in this organism.Katy PoncinAgnès RobaRavikumar JimmidiGeorges PotembergAntonella FioravantiNayla FrancisKévin WillemartNicolas ZeippenArnaud MachelartEmanuele G. BiondiEric MurailleStéphane P. VincentXavier De BolleNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katy Poncin Agnès Roba Ravikumar Jimmidi Georges Potemberg Antonella Fioravanti Nayla Francis Kévin Willemart Nicolas Zeippen Arnaud Machelart Emanuele G. Biondi Eric Muraille Stéphane P. Vincent Xavier De Bolle Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
description	It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the pathways required for DNA repair in this organism.
format	article
author	Katy Poncin Agnès Roba Ravikumar Jimmidi Georges Potemberg Antonella Fioravanti Nayla Francis Kévin Willemart Nicolas Zeippen Arnaud Machelart Emanuele G. Biondi Eric Muraille Stéphane P. Vincent Xavier De Bolle
author_facet	Katy Poncin Agnès Roba Ravikumar Jimmidi Georges Potemberg Antonella Fioravanti Nayla Francis Kévin Willemart Nicolas Zeippen Arnaud Machelart Emanuele G. Biondi Eric Muraille Stéphane P. Vincent Xavier De Bolle
author_sort	Katy Poncin
title	Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
title_short	Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
title_full	Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
title_fullStr	Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
title_full_unstemmed	Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus
title_sort	occurrence and repair of alkylating stress in the intracellular pathogen brucella abortus
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac
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Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

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