Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis

Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis

Abstract Background We have recently demonstrated that serum CCL20 levels positively correlate with mean pulmonary arterial pressure in patients with systemic sclerosis (SSc). Considering a proangiogenic effect of CCL20 on endothelial cells via CCR6, the CCL20/CCR6 axis may contribute to the develop...

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Bibliographic Details
Main Authors: Tetsuya Ikawa, Takuya Miyagawa, Yuki Fukui, Satoshi Toyama, Jun Omatsu, Kentaro Awaji, Yuta Norimatsu, Yusuke Watanabe, Ayumi Yoshizaki, Shinichi Sato, Yoshihide Asano
Format: article
Language:EN
Published: BMC 2021
Subjects:
Systemic sclerosis
CCL20
CCR6
FLI1
Endothelial cells
Diseases of the musculoskeletal system
RC925-935
Online Access:https://doaj.org/article/0e9cdce30672437283f148d5d64ac7bc
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https://doaj.org/article/0e9cdce30672437283f148d5d64ac7bc

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