Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds

Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds

The direct cleavage of C(CO)−C single bonds is usually restricted to strained ketone substrates or to chelating assistance. Here, the authors show a rhodium(II)-catalyzed three-component reaction of 1,3-diones, diazoesters, and DMF, leading to an unusual formal insertion of O–C(sp3)–C(sp2) into unst...

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Autores principales: Dan Ba, Si Wen, Qingyu Tian, Yanhui Chen, Weiwei Lv, Guolin Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0ea7198f1b3b44dba9647247a33a867d
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spelling oai:doaj.org-article:0ea7198f1b3b44dba9647247a33a867d2021-12-02T16:35:13ZRhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds10.1038/s41467-020-17990-z2041-1723https://doaj.org/article/0ea7198f1b3b44dba9647247a33a867d2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17990-zhttps://doaj.org/toc/2041-1723The direct cleavage of C(CO)−C single bonds is usually restricted to strained ketone substrates or to chelating assistance. Here, the authors show a rhodium(II)-catalyzed three-component reaction of 1,3-diones, diazoesters, and DMF, leading to an unusual formal insertion of O–C(sp3)–C(sp2) into unstrained C(CO)–C bonds.Dan BaSi WenQingyu TianYanhui ChenWeiwei LvGuolin ChengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dan Ba
Si Wen
Qingyu Tian
Yanhui Chen
Weiwei Lv
Guolin Cheng
Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
description The direct cleavage of C(CO)−C single bonds is usually restricted to strained ketone substrates or to chelating assistance. Here, the authors show a rhodium(II)-catalyzed three-component reaction of 1,3-diones, diazoesters, and DMF, leading to an unusual formal insertion of O–C(sp3)–C(sp2) into unstrained C(CO)–C bonds.
format article
author Dan Ba
Si Wen
Qingyu Tian
Yanhui Chen
Weiwei Lv
Guolin Cheng
author_facet Dan Ba
Si Wen
Qingyu Tian
Yanhui Chen
Weiwei Lv
Guolin Cheng
author_sort Dan Ba
title Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
title_short Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
title_full Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
title_fullStr Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
title_full_unstemmed Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds
title_sort rhodium(ii)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of o–c(sp3)–c(sp2) into c–c bonds
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/0ea7198f1b3b44dba9647247a33a867d
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