Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The OX40-OX40L axis is a crucial component of the costimulatory requirement of CD4 T cell responses. Here, the authors show context and cell type specific expression of OX40L for driving Th1 cell generation during acute and chronic models of infection.

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Autores principales:	Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0ea90bbafd214ffb93f45a5e4c9d3fb6
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spelling	oai:doaj.org-article:0ea90bbafd214ffb93f45a5e4c9d3fb62021-12-02T18:34:07ZTh1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues10.1038/s41467-020-17293-32041-1723https://doaj.org/article/0ea90bbafd214ffb93f45a5e4c9d3fb62020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17293-3https://doaj.org/toc/2041-1723The OX40-OX40L axis is a crucial component of the costimulatory requirement of CD4 T cell responses. Here, the authors show context and cell type specific expression of OX40L for driving Th1 cell generation during acute and chronic models of infection.Dominika W. GajdasikFabrina GaspalEmily E. HalfordRemi FiancetteEmma E. DuttonClaire WillisTimo RückertChiara RomagnaniAudrey GerardSarah L. BevingtonAndrew S. MacDonaldMarina BottoTimothy VyseDavid R. WithersNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dominika W. Gajdasik Fabrina Gaspal Emily E. Halford Remi Fiancette Emma E. Dutton Claire Willis Timo Rückert Chiara Romagnani Audrey Gerard Sarah L. Bevington Andrew S. MacDonald Marina Botto Timothy Vyse David R. Withers Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
description	The OX40-OX40L axis is a crucial component of the costimulatory requirement of CD4 T cell responses. Here, the authors show context and cell type specific expression of OX40L for driving Th1 cell generation during acute and chronic models of infection.
format	article
author	Dominika W. Gajdasik Fabrina Gaspal Emily E. Halford Remi Fiancette Emma E. Dutton Claire Willis Timo Rückert Chiara Romagnani Audrey Gerard Sarah L. Bevington Andrew S. MacDonald Marina Botto Timothy Vyse David R. Withers
author_facet	Dominika W. Gajdasik Fabrina Gaspal Emily E. Halford Remi Fiancette Emma E. Dutton Claire Willis Timo Rückert Chiara Romagnani Audrey Gerard Sarah L. Bevington Andrew S. MacDonald Marina Botto Timothy Vyse David R. Withers
author_sort	Dominika W. Gajdasik
title	Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
title_short	Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
title_full	Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
title_fullStr	Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
title_full_unstemmed	Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
title_sort	th1 responses in vivo require cell-specific provision of ox40l dictated by environmental cues
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/0ea90bbafd214ffb93f45a5e4c9d3fb6
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Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

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