Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

The OX40-OX40L axis is a crucial component of the costimulatory requirement of CD4 T cell responses. Here, the authors show context and cell type specific expression of OX40L for driving Th1 cell generation during acute and chronic models of infection.

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Detalles Bibliográficos
Autores principales: Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/0ea90bbafd214ffb93f45a5e4c9d3fb6
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