DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli

Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.

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Autores principales: Patricia L. Foster, Brittany A. Niccum, Heewook Lee
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/0eadf6700b8040838b46ddea31c9abb7
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spelling oai:doaj.org-article:0eadf6700b8040838b46ddea31c9abb72021-11-03T21:52:35ZDNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli2150-751110.1128/mBio.02503-21https://doaj.org/article/0eadf6700b8040838b46ddea31c9abb72021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02503-21https://doaj.org/toc/2150-7511 Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.Patricia L. FosterBrittany A. NiccumHeewook LeeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Patricia L. Foster
Brittany A. Niccum
Heewook Lee
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
description Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.
format article
author Patricia L. Foster
Brittany A. Niccum
Heewook Lee
author_facet Patricia L. Foster
Brittany A. Niccum
Heewook Lee
author_sort Patricia L. Foster
title DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
title_short DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
title_full DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
title_fullStr DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
title_full_unstemmed DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
title_sort dna replication-transcription conflicts do not significantly contribute to spontaneous mutations due to replication errors in escherichia coli
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/0eadf6700b8040838b46ddea31c9abb7
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AT brittanyaniccum dnareplicationtranscriptionconflictsdonotsignificantlycontributetospontaneousmutationsduetoreplicationerrorsinescherichiacoli
AT heewooklee dnareplicationtranscriptionconflictsdonotsignificantlycontributetospontaneousmutationsduetoreplicationerrorsinescherichiacoli
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