DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli
Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.
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American Society for Microbiology
2021
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oai:doaj.org-article:0eadf6700b8040838b46ddea31c9abb72021-11-03T21:52:35ZDNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli2150-751110.1128/mBio.02503-21https://doaj.org/article/0eadf6700b8040838b46ddea31c9abb72021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02503-21https://doaj.org/toc/2150-7511 Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur.Patricia L. FosterBrittany A. NiccumHeewook LeeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
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DOAJ |
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EN |
topic |
Microbiology QR1-502 |
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Microbiology QR1-502 Patricia L. Foster Brittany A. Niccum Heewook Lee DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
description |
Because DNA replication and transcription occur on the same DNA template, encounters between the two machines occur frequently. When these encounters are head-to-head, genomic disruption can occur. |
format |
article |
author |
Patricia L. Foster Brittany A. Niccum Heewook Lee |
author_facet |
Patricia L. Foster Brittany A. Niccum Heewook Lee |
author_sort |
Patricia L. Foster |
title |
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
title_short |
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
title_full |
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
title_fullStr |
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
title_full_unstemmed |
DNA Replication-Transcription Conflicts Do Not Significantly Contribute to Spontaneous Mutations Due to Replication Errors in Escherichia coli |
title_sort |
dna replication-transcription conflicts do not significantly contribute to spontaneous mutations due to replication errors in escherichia coli |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/0eadf6700b8040838b46ddea31c9abb7 |
work_keys_str_mv |
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_version_ |
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