Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis
Introduction: COVID-19 has affected the pattern of referral to medical centers and quarantine against COVID-19 might delay referral and management of surgical emergencies. This study aimed to compare the pooled event rate of pediatric perforated appendicitis before and during the COVID-19 pandemic....
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Shahid Beheshti University of Medical Sciences
2022
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oai:doaj.org-article:0eae41221de64777b8c9bd209b81f9182021-11-27T09:13:46ZIncidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis10.22037/aaem.v10i1.14212645-4904https://doaj.org/article/0eae41221de64777b8c9bd209b81f9182022-01-01T00:00:00Zhttps://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1421https://doaj.org/toc/2645-4904 Introduction: COVID-19 has affected the pattern of referral to medical centers and quarantine against COVID-19 might delay referral and management of surgical emergencies. This study aimed to compare the pooled event rate of pediatric perforated appendicitis before and during the COVID-19 pandemic. Methods: This was a systematic review and meta-analysis study based on the PRISMA guidelines. Scopus, Web of Sciences, and PubMed databases were searched for studies reporting the rate of perforated appendicitis based on the post-appendectomy observations or imaging methods. The Egger bias test and funnel plot were used to detect and depict publication bias. Statistical analysis was performed in Comprehensive Meta-analysis package version 3. Results: Twelve studies were eligible for inclusion in our study. The pooled prevalence of pediatric perforated appendicitis in the pre-COVID era was 28.5% (CI95%: 28.3 to 28.7%) with a heterogeneity of 99%. In the COVID era, the event rate proportion was 39.4% (CI95%: 36.6 to 42.3%) with a heterogeneity of 99%. There was a significant difference in the subgroup analysis within the pre-COVID and COVID era (P<0.001), showing a higher perforation rate in the COVID era. Conclusion: Our study showed that during the COVID-19 pandemic, the rate of perforated appendicitis has significantly increased in comparison to before the COVID-19 pandemic. Gholamreza MotazedianPoorya AryanpoorEhsan RahmanianSamaneh AbiriNavid KalaniNaser HatamiFarhad BagherianMohammad EtezadpourRoohie FarzanehFatemeh MalekiMahdi ForoughianMojtaba GhaediShahid Beheshti University of Medical SciencesarticleCOVID-19AppendicitisRupturedAbdomen, AcuteMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENArchives of Academic Emergency Medicine, Vol 10, Iss 1 (2022) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
COVID-19 Appendicitis Ruptured Abdomen, Acute Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 |
| spellingShingle |
COVID-19 Appendicitis Ruptured Abdomen, Acute Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Gholamreza Motazedian Poorya Aryanpoor Ehsan Rahmanian Samaneh Abiri Navid Kalani Naser Hatami Farhad Bagherian Mohammad Etezadpour Roohie Farzaneh Fatemeh Maleki Mahdi Foroughian Mojtaba Ghaedi Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| description |
Introduction: COVID-19 has affected the pattern of referral to medical centers and quarantine against COVID-19 might delay referral and management of surgical emergencies. This study aimed to compare the pooled event rate of pediatric perforated appendicitis before and during the COVID-19 pandemic.
Methods: This was a systematic review and meta-analysis study based on the PRISMA guidelines. Scopus, Web of Sciences, and PubMed databases were searched for studies reporting the rate of perforated appendicitis based on the post-appendectomy observations or imaging methods. The Egger bias test and funnel plot were used to detect and depict publication bias. Statistical analysis was performed in Comprehensive Meta-analysis package version 3.
Results: Twelve studies were eligible for inclusion in our study. The pooled prevalence of pediatric perforated appendicitis in the pre-COVID era was 28.5% (CI95%: 28.3 to 28.7%) with a heterogeneity of 99%. In the COVID era, the event rate proportion was 39.4% (CI95%: 36.6 to 42.3%) with a heterogeneity of 99%. There was a significant difference in the subgroup analysis within the pre-COVID and COVID era (P<0.001), showing a higher perforation rate in the COVID era.
Conclusion: Our study showed that during the COVID-19 pandemic, the rate of perforated appendicitis has significantly increased in comparison to before the COVID-19 pandemic.
|
| format |
article |
| author |
Gholamreza Motazedian Poorya Aryanpoor Ehsan Rahmanian Samaneh Abiri Navid Kalani Naser Hatami Farhad Bagherian Mohammad Etezadpour Roohie Farzaneh Fatemeh Maleki Mahdi Foroughian Mojtaba Ghaedi |
| author_facet |
Gholamreza Motazedian Poorya Aryanpoor Ehsan Rahmanian Samaneh Abiri Navid Kalani Naser Hatami Farhad Bagherian Mohammad Etezadpour Roohie Farzaneh Fatemeh Maleki Mahdi Foroughian Mojtaba Ghaedi |
| author_sort |
Gholamreza Motazedian |
| title |
Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| title_short |
Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| title_full |
Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| title_fullStr |
Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| title_full_unstemmed |
Incidence of Pediatric Perforated Appendicitis during the COVID-19 Pandemic; a Systematic Review and Meta-Analysis |
| title_sort |
incidence of pediatric perforated appendicitis during the covid-19 pandemic; a systematic review and meta-analysis |
| publisher |
Shahid Beheshti University of Medical Sciences |
| publishDate |
2022 |
| url |
https://doaj.org/article/0eae41221de64777b8c9bd209b81f918 |
| work_keys_str_mv |
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