A single-cell atlas and lineage analysis of the adult Drosophila ovary

Cell types in the adult Drosophila ovary vary during homeostasis and differing environmental conditions. Here, the authors use single-cell RNA-sequencing to identify 26 ovarian cell populations and show cellular plasticity in which escort cells can convert to follicle stem cells upon starvation.

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Autores principales: Katja Rust, Laurean E. Byrnes, Kevin Shengyang Yu, Jason S. Park, Julie B. Sneddon, Aaron D. Tward, Todd G. Nystul
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0eaef62658824320bc54d66d962eb742
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spelling oai:doaj.org-article:0eaef62658824320bc54d66d962eb7422021-12-02T17:31:10ZA single-cell atlas and lineage analysis of the adult Drosophila ovary10.1038/s41467-020-19361-02041-1723https://doaj.org/article/0eaef62658824320bc54d66d962eb7422020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19361-0https://doaj.org/toc/2041-1723Cell types in the adult Drosophila ovary vary during homeostasis and differing environmental conditions. Here, the authors use single-cell RNA-sequencing to identify 26 ovarian cell populations and show cellular plasticity in which escort cells can convert to follicle stem cells upon starvation.Katja RustLaurean E. ByrnesKevin Shengyang YuJason S. ParkJulie B. SneddonAaron D. TwardTodd G. NystulNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katja Rust
Laurean E. Byrnes
Kevin Shengyang Yu
Jason S. Park
Julie B. Sneddon
Aaron D. Tward
Todd G. Nystul
A single-cell atlas and lineage analysis of the adult Drosophila ovary
description Cell types in the adult Drosophila ovary vary during homeostasis and differing environmental conditions. Here, the authors use single-cell RNA-sequencing to identify 26 ovarian cell populations and show cellular plasticity in which escort cells can convert to follicle stem cells upon starvation.
format article
author Katja Rust
Laurean E. Byrnes
Kevin Shengyang Yu
Jason S. Park
Julie B. Sneddon
Aaron D. Tward
Todd G. Nystul
author_facet Katja Rust
Laurean E. Byrnes
Kevin Shengyang Yu
Jason S. Park
Julie B. Sneddon
Aaron D. Tward
Todd G. Nystul
author_sort Katja Rust
title A single-cell atlas and lineage analysis of the adult Drosophila ovary
title_short A single-cell atlas and lineage analysis of the adult Drosophila ovary
title_full A single-cell atlas and lineage analysis of the adult Drosophila ovary
title_fullStr A single-cell atlas and lineage analysis of the adult Drosophila ovary
title_full_unstemmed A single-cell atlas and lineage analysis of the adult Drosophila ovary
title_sort single-cell atlas and lineage analysis of the adult drosophila ovary
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/0eaef62658824320bc54d66d962eb742
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