Genome-wide signatures of 'rearrangement hotspots' within segmental duplications in humans.
The primary objective of this study was to create a genome-wide high resolution map (i.e., >100 bp) of 'rearrangement hotspots' which can facilitate the identification of regions capable of mediating de novo deletions or duplications in humans. A hierarchical method was employed to frag...
Guardado en:
Autores principales: | Mohammed Uddin, Mitch Sturge, Lynette Peddle, Darren D O'Rielly, Proton Rahman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0ebc5dec960549d288d1a45b6d873a7a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer
por: Rui Xing, et al.
Publicado: (2019) -
Segmental Duplication of Chromosome 11 and its Implications for Cell Division and Genome-wide Expression in Rice
por: Rong Zhang, et al.
Publicado: (2017) -
Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis
por: Sara Rahmati, et al.
Publicado: (2020) -
Eroded telomeres are rearranged in quiescent fission yeast cells through duplications of subtelomeric sequences
por: Laetitia Maestroni, et al.
Publicado: (2017) -
Neonatal enteric duplication cyst with segmental gut volvulus
por: Syed Waqas Ali, et al.
Publicado: (2021)