Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae

DNA polymerases δ and ε (Pols δ and ε) are thought to be responsible for lagging and leading strand synthesis, respectively. Here the authors present evidence that Pol δ contributes to the initiation of leading strand replication in budding yeast by synthesizing DNA of both strands at replication or...

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Autores principales:	Marta A. Garbacz, Scott A. Lujan, Adam B. Burkholder, Phillip B. Cox, Qiuqin Wu, Zhi-Xiong Zhou, James E. Haber, Thomas A. Kunkel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/0ec48e9ef60b4225a524868988d1cef0
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spelling	oai:doaj.org-article:0ec48e9ef60b4225a524868988d1cef02021-12-02T17:33:06ZEvidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae10.1038/s41467-018-03270-42041-1723https://doaj.org/article/0ec48e9ef60b4225a524868988d1cef02018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03270-4https://doaj.org/toc/2041-1723DNA polymerases δ and ε (Pols δ and ε) are thought to be responsible for lagging and leading strand synthesis, respectively. Here the authors present evidence that Pol δ contributes to the initiation of leading strand replication in budding yeast by synthesizing DNA of both strands at replication origins.Marta A. GarbaczScott A. LujanAdam B. BurkholderPhillip B. CoxQiuqin WuZhi-Xiong ZhouJames E. HaberThomas A. KunkelNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marta A. Garbacz Scott A. Lujan Adam B. Burkholder Phillip B. Cox Qiuqin Wu Zhi-Xiong Zhou James E. Haber Thomas A. Kunkel Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
description	DNA polymerases δ and ε (Pols δ and ε) are thought to be responsible for lagging and leading strand synthesis, respectively. Here the authors present evidence that Pol δ contributes to the initiation of leading strand replication in budding yeast by synthesizing DNA of both strands at replication origins.
format	article
author	Marta A. Garbacz Scott A. Lujan Adam B. Burkholder Phillip B. Cox Qiuqin Wu Zhi-Xiong Zhou James E. Haber Thomas A. Kunkel
author_facet	Marta A. Garbacz Scott A. Lujan Adam B. Burkholder Phillip B. Cox Qiuqin Wu Zhi-Xiong Zhou James E. Haber Thomas A. Kunkel
author_sort	Marta A. Garbacz
title	Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
title_short	Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
title_full	Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
title_fullStr	Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
title_full_unstemmed	Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
title_sort	evidence that dna polymerase δ contributes to initiating leading strand dna replication in saccharomyces cerevisiae
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/0ec48e9ef60b4225a524868988d1cef0
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Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae

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