Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae

DNA polymerases δ and ε (Pols δ and ε) are thought to be responsible for lagging and leading strand synthesis, respectively. Here the authors present evidence that Pol δ contributes to the initiation of leading strand replication in budding yeast by synthesizing DNA of both strands at replication or...

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Autores principales: Marta A. Garbacz, Scott A. Lujan, Adam B. Burkholder, Phillip B. Cox, Qiuqin Wu, Zhi-Xiong Zhou, James E. Haber, Thomas A. Kunkel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0ec48e9ef60b4225a524868988d1cef0
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