High-throughput immune repertoire analysis with IGoR

B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.

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Autores principales: Quentin Marcou, Thierry Mora, Aleksandra M. Walczak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0ed29de96e8f4e7995e61fd3999c3c6e
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spelling oai:doaj.org-article:0ed29de96e8f4e7995e61fd3999c3c6e2021-12-02T13:27:31ZHigh-throughput immune repertoire analysis with IGoR10.1038/s41467-018-02832-w2041-1723https://doaj.org/article/0ed29de96e8f4e7995e61fd3999c3c6e2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02832-whttps://doaj.org/toc/2041-1723B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.Quentin MarcouThierry MoraAleksandra M. WalczakNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Quentin Marcou
Thierry Mora
Aleksandra M. Walczak
High-throughput immune repertoire analysis with IGoR
description B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.
format article
author Quentin Marcou
Thierry Mora
Aleksandra M. Walczak
author_facet Quentin Marcou
Thierry Mora
Aleksandra M. Walczak
author_sort Quentin Marcou
title High-throughput immune repertoire analysis with IGoR
title_short High-throughput immune repertoire analysis with IGoR
title_full High-throughput immune repertoire analysis with IGoR
title_fullStr High-throughput immune repertoire analysis with IGoR
title_full_unstemmed High-throughput immune repertoire analysis with IGoR
title_sort high-throughput immune repertoire analysis with igor
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0ed29de96e8f4e7995e61fd3999c3c6e
work_keys_str_mv AT quentinmarcou highthroughputimmunerepertoireanalysiswithigor
AT thierrymora highthroughputimmunerepertoireanalysiswithigor
AT aleksandramwalczak highthroughputimmunerepertoireanalysiswithigor
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