Analog insulin detemir for patients with type 1 and type 2 diabetes: a review

Gregory&nbsp;E PetersonDepartment of Internal Medicine, Des Moines University, USAObjective: To review insulin detemir for clinical use to better manage patients with type 1 and type 2 diabetes.Methods: A MEDLINE search, in English, from June 30, 2006 to December 1, 2008, using the terms &am...

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Autor principal:	Gregory E Peterson
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/0ed4823db64e443997f6940b7a08960c
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spelling	oai:doaj.org-article:0ed4823db64e443997f6940b7a08960c2021-12-02T01:11:43ZAnalog insulin detemir for patients with type 1 and type 2 diabetes: a review1178-7007https://doaj.org/article/0ed4823db64e443997f6940b7a08960c2009-05-01T00:00:00Zhttp://www.dovepress.com/analog-insulin-detemir-for-patients-with-type-1-and-type-2-diabetes-a--a3138https://doaj.org/toc/1178-7007Gregory&nbsp;E PetersonDepartment of Internal Medicine, Des Moines University, USAObjective: To review insulin detemir for clinical use to better manage patients with type 1 and type 2 diabetes.Methods: A MEDLINE search, in English, from June 30, 2006 to December 1, 2008, using the terms &ldquo;insulin analogs,&rdquo; &ldquo;insulin detemir&rdquo; and &ldquo;long-acting insulin analog.&rdquo;Results: Insulin detemir improves glycemic control, based on HbA1C reduction and fasting glucose levels, without increasing the risk of hypoglycemia and weight gain. Insulin detemir has lower glycemic variability, with less intra-subject variability in blood glucose levels in patients with type 1 and type 2 diabetes, without increasing the risk of hypoglycemia. When added to oral anti-diabetes agents (OADs) in type 2 diabetes, insulin detemir demonstrates superiority to other basal insulin options.Conclusion: Insulin detemir appears to provide better glycemic control with a lower risk of hypoglycemia and less weight gain in the treatment of patients with type 1 and type 2 diabetes.Keywords: type 1 diabetes, type 2 diabetes, insulin analogs, insulin detemir Gregory E PetersonDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2009, Iss default, Pp 31-36 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Gregory E Peterson Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
description	Gregory&nbsp;E PetersonDepartment of Internal Medicine, Des Moines University, USAObjective: To review insulin detemir for clinical use to better manage patients with type 1 and type 2 diabetes.Methods: A MEDLINE search, in English, from June 30, 2006 to December 1, 2008, using the terms &ldquo;insulin analogs,&rdquo; &ldquo;insulin detemir&rdquo; and &ldquo;long-acting insulin analog.&rdquo;Results: Insulin detemir improves glycemic control, based on HbA1C reduction and fasting glucose levels, without increasing the risk of hypoglycemia and weight gain. Insulin detemir has lower glycemic variability, with less intra-subject variability in blood glucose levels in patients with type 1 and type 2 diabetes, without increasing the risk of hypoglycemia. When added to oral anti-diabetes agents (OADs) in type 2 diabetes, insulin detemir demonstrates superiority to other basal insulin options.Conclusion: Insulin detemir appears to provide better glycemic control with a lower risk of hypoglycemia and less weight gain in the treatment of patients with type 1 and type 2 diabetes.Keywords: type 1 diabetes, type 2 diabetes, insulin analogs, insulin detemir
format	article
author	Gregory E Peterson
author_facet	Gregory E Peterson
author_sort	Gregory E Peterson
title	Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
title_short	Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
title_full	Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
title_fullStr	Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
title_full_unstemmed	Analog insulin detemir for patients with type 1 and type 2 diabetes: a review
title_sort	analog insulin detemir for patients with type 1 and type 2 diabetes: a review
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/0ed4823db64e443997f6940b7a08960c
work_keys_str_mv	AT gregoryepeterson analoginsulindetemirforpatientswithtype1andtype2diabetesareview
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Analog insulin detemir for patients with type 1 and type 2 diabetes: a review

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