Ultra-strong bio-glue from genetically engineered polypeptides

Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models...

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Autores principales: Chao Ma, Jing Sun, Bo Li, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert Gӧstl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu, Andreas Herrmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0eddeb95f0a14c6b90ee911d32d65f9b
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Sumario:Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.