Ultra-strong bio-glue from genetically engineered polypeptides

Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models...

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Autores principales: Chao Ma, Jing Sun, Bo Li, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert Gӧstl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu, Andreas Herrmann
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0eddeb95f0a14c6b90ee911d32d65f9b
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spelling oai:doaj.org-article:0eddeb95f0a14c6b90ee911d32d65f9b2021-12-02T16:04:29ZUltra-strong bio-glue from genetically engineered polypeptides10.1038/s41467-021-23117-92041-1723https://doaj.org/article/0eddeb95f0a14c6b90ee911d32d65f9b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23117-9https://doaj.org/toc/2041-1723Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.Chao MaJing SunBo LiYang FengYao SunLi XiangBaiheng WuLingling XiaoBaimei LiuVladislav S. PetrovskiiBin LiuJinrui ZhangZili WangHongyan LiLei ZhangJingjing LiFan WangRobert GӧstlIgor I. PotemkinDong ChenHongbo ZengHongjie ZhangKai LiuAndreas HerrmannNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chao Ma
Jing Sun
Bo Li
Yang Feng
Yao Sun
Li Xiang
Baiheng Wu
Lingling Xiao
Baimei Liu
Vladislav S. Petrovskii
Bin Liu
Jinrui Zhang
Zili Wang
Hongyan Li
Lei Zhang
Jingjing Li
Fan Wang
Robert Gӧstl
Igor I. Potemkin
Dong Chen
Hongbo Zeng
Hongjie Zhang
Kai Liu
Andreas Herrmann
Ultra-strong bio-glue from genetically engineered polypeptides
description Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.
format article
author Chao Ma
Jing Sun
Bo Li
Yang Feng
Yao Sun
Li Xiang
Baiheng Wu
Lingling Xiao
Baimei Liu
Vladislav S. Petrovskii
Bin Liu
Jinrui Zhang
Zili Wang
Hongyan Li
Lei Zhang
Jingjing Li
Fan Wang
Robert Gӧstl
Igor I. Potemkin
Dong Chen
Hongbo Zeng
Hongjie Zhang
Kai Liu
Andreas Herrmann
author_facet Chao Ma
Jing Sun
Bo Li
Yang Feng
Yao Sun
Li Xiang
Baiheng Wu
Lingling Xiao
Baimei Liu
Vladislav S. Petrovskii
Bin Liu
Jinrui Zhang
Zili Wang
Hongyan Li
Lei Zhang
Jingjing Li
Fan Wang
Robert Gӧstl
Igor I. Potemkin
Dong Chen
Hongbo Zeng
Hongjie Zhang
Kai Liu
Andreas Herrmann
author_sort Chao Ma
title Ultra-strong bio-glue from genetically engineered polypeptides
title_short Ultra-strong bio-glue from genetically engineered polypeptides
title_full Ultra-strong bio-glue from genetically engineered polypeptides
title_fullStr Ultra-strong bio-glue from genetically engineered polypeptides
title_full_unstemmed Ultra-strong bio-glue from genetically engineered polypeptides
title_sort ultra-strong bio-glue from genetically engineered polypeptides
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/0eddeb95f0a14c6b90ee911d32d65f9b
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