Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome.

Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome.

<h4>Background</h4>Irritable bowel syndrome (IBS) is largely viewed as a stress-related disorder caused by aberrant brain-gut-immune communication and altered gastrointestinal (GI) homeostasis. Accumulating evidence demonstrates that stress modulates innate immune responses; however, ver...

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Autores principales: Declan P McKernan, Aoife Nolan, Elizabeth K Brint, Siobhain M O'Mahony, Niall P Hyland, John F Cryan, Timothy G Dinan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/0ee5709c37c64f76ac4beb5946299e1b
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