ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD

Conventional strategies for cancer treatment are close to their efficiency limits. Meanwhile, rapid development of experimental immunology and immunotherapy led to first successful experiences in antitumor vaccination. Over last decade, remarkable results were obtained by means of anticancer vaccina...

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Autores principales: M. V. Stegantseva, A. N. Meleshko
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2017
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Acceso en línea:https://doaj.org/article/0ee78b693cbc45f9a7fe896340a2e588
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spelling oai:doaj.org-article:0ee78b693cbc45f9a7fe896340a2e5882021-11-18T08:03:46ZANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD1563-06252313-741X10.15789/1563-0625-2017-2-145-156https://doaj.org/article/0ee78b693cbc45f9a7fe896340a2e5882017-05-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1227https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XConventional strategies for cancer treatment are close to their efficiency limits. Meanwhile, rapid development of experimental immunology and immunotherapy led to first successful experiences in antitumor vaccination. Over last decade, remarkable results were obtained by means of anticancer vaccination being implemented into clinical settings thus causing popularity and growth of interest to tumor-specific DNA vaccines. In this review, we discuss basic principles of a DNA vaccine construction, their structural characteristics and diversity, mechanisms of their biological action, pharmaceutical forms and delivery routes into the body.M. V. StegantsevaA. N. MeleshkoSPb RAACIarticleoncologyimmunotherapyantigensvaccineantitumor immunityImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 19, Iss 2, Pp 145-156 (2017)
institution DOAJ
collection DOAJ
language RU
topic oncology
immunotherapy
antigens
vaccine
antitumor immunity
Immunologic diseases. Allergy
RC581-607
spellingShingle oncology
immunotherapy
antigens
vaccine
antitumor immunity
Immunologic diseases. Allergy
RC581-607
M. V. Stegantseva
A. N. Meleshko
ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
description Conventional strategies for cancer treatment are close to their efficiency limits. Meanwhile, rapid development of experimental immunology and immunotherapy led to first successful experiences in antitumor vaccination. Over last decade, remarkable results were obtained by means of anticancer vaccination being implemented into clinical settings thus causing popularity and growth of interest to tumor-specific DNA vaccines. In this review, we discuss basic principles of a DNA vaccine construction, their structural characteristics and diversity, mechanisms of their biological action, pharmaceutical forms and delivery routes into the body.
format article
author M. V. Stegantseva
A. N. Meleshko
author_facet M. V. Stegantseva
A. N. Meleshko
author_sort M. V. Stegantseva
title ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
title_short ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
title_full ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
title_fullStr ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
title_full_unstemmed ANTICANCER DNA VACCINATION: PRINCIPLE AND PERSPECTIVES OF THE METHOD
title_sort anticancer dna vaccination: principle and perspectives of the method
publisher SPb RAACI
publishDate 2017
url https://doaj.org/article/0ee78b693cbc45f9a7fe896340a2e588
work_keys_str_mv AT mvstegantseva anticancerdnavaccinationprincipleandperspectivesofthemethod
AT anmeleshko anticancerdnavaccinationprincipleandperspectivesofthemethod
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