Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming.

<h4>Aims/hypothesis</h4>Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogrammin...

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Autores principales: Nathalie Swales, Geert A Martens, Stefan Bonné, Yves Heremans, Rehannah Borup, Mark Van de Casteele, Zhidong Ling, Daniel Pipeleers, Philippe Ravassard, Finn Nielsen, Jorge Ferrer, Harry Heimberg
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/0eea1d198a354a35ad5881ce7c8b0b0b
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