An alternative food source for metabolism and longevity studies in Caenorhabditis elegans
Beydoun, Choi et al. develop a metabolically inactive food source for C. elegans worms that minimizes the confounding effects of bacterial metabolism on worm metabolism and aging. They find that worms eat and grow well on a paraformaldehyde (PFA)-treated E. coli food source, recommending the use of...
Guardado en:
Autores principales: | , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0eeff3968ef44f02a9f5c443b0a3f8f5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0eeff3968ef44f02a9f5c443b0a3f8f5 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0eeff3968ef44f02a9f5c443b0a3f8f52021-12-02T13:20:00ZAn alternative food source for metabolism and longevity studies in Caenorhabditis elegans10.1038/s42003-021-01764-42399-3642https://doaj.org/article/0eeff3968ef44f02a9f5c443b0a3f8f52021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01764-4https://doaj.org/toc/2399-3642Beydoun, Choi et al. develop a metabolically inactive food source for C. elegans worms that minimizes the confounding effects of bacterial metabolism on worm metabolism and aging. They find that worms eat and grow well on a paraformaldehyde (PFA)-treated E. coli food source, recommending the use of 0.5% PFA-killed bacteria as a nematode food source for metabolic experiments.Safa BeydounHyo Sub ChoiGabrielle Dela-CruzJoseph KruempelShijiao HuangDaphne BazopoulouHillary A. MillerMegan L. SchallerCharles R. EvansScott F. LeiserNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Biology (General) QH301-705.5 |
spellingShingle |
Biology (General) QH301-705.5 Safa Beydoun Hyo Sub Choi Gabrielle Dela-Cruz Joseph Kruempel Shijiao Huang Daphne Bazopoulou Hillary A. Miller Megan L. Schaller Charles R. Evans Scott F. Leiser An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
description |
Beydoun, Choi et al. develop a metabolically inactive food source for C. elegans worms that minimizes the confounding effects of bacterial metabolism on worm metabolism and aging. They find that worms eat and grow well on a paraformaldehyde (PFA)-treated E. coli food source, recommending the use of 0.5% PFA-killed bacteria as a nematode food source for metabolic experiments. |
format |
article |
author |
Safa Beydoun Hyo Sub Choi Gabrielle Dela-Cruz Joseph Kruempel Shijiao Huang Daphne Bazopoulou Hillary A. Miller Megan L. Schaller Charles R. Evans Scott F. Leiser |
author_facet |
Safa Beydoun Hyo Sub Choi Gabrielle Dela-Cruz Joseph Kruempel Shijiao Huang Daphne Bazopoulou Hillary A. Miller Megan L. Schaller Charles R. Evans Scott F. Leiser |
author_sort |
Safa Beydoun |
title |
An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
title_short |
An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
title_full |
An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
title_fullStr |
An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
title_full_unstemmed |
An alternative food source for metabolism and longevity studies in Caenorhabditis elegans |
title_sort |
alternative food source for metabolism and longevity studies in caenorhabditis elegans |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/0eeff3968ef44f02a9f5c443b0a3f8f5 |
work_keys_str_mv |
AT safabeydoun analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT hyosubchoi analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT gabrielledelacruz analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT josephkruempel analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT shijiaohuang analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT daphnebazopoulou analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT hillaryamiller analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT meganlschaller analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT charlesrevans analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT scottfleiser analternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT safabeydoun alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT hyosubchoi alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT gabrielledelacruz alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT josephkruempel alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT shijiaohuang alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT daphnebazopoulou alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT hillaryamiller alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT meganlschaller alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT charlesrevans alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans AT scottfleiser alternativefoodsourceformetabolismandlongevitystudiesincaenorhabditiselegans |
_version_ |
1718393253816958976 |