Tescalcin/c-Src/IGF1Rβ-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1

Abstract Tescalcin (TESC; also known as calcineurin B homologous protein 3, CHP3) has recently reported as a regulator of cancer progression. Here, we showed that the elevation of TESC in non-small cell lung cancer (NSCLC) intensifies epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jei Ha Lee, Soo Im Choi, Rae Kwon Kim, Eun Wie Cho, In Gyu Kim
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/0ef08a7a1b0645949972a3ac06bfbd68
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!