Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?

The modern algorithm of hypoglycemic therapy for patients with type 2 diabetes mellitus (DM2) has been designed to effectively reach the ?target?blood glucose and HbA1c levels associated with the lowest mortality rate.The most popular scheme is combined treatment with metformin andsulfonylureasthatm...

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Autores principales: Andrey Alexeevich Aleksandrov, Svetlana Semenovna Kukharenko, Maria Nikolaevna Yadrikhinskaya
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Publicado: Endocrinology Research Centre 2010
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spelling oai:doaj.org-article:0ef17485173f4d6dba361fd590ee94272021-11-14T09:00:15ZCardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?2072-03512072-037810.14341/2072-0351-6054https://doaj.org/article/0ef17485173f4d6dba361fd590ee94272010-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6054https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378The modern algorithm of hypoglycemic therapy for patients with type 2 diabetes mellitus (DM2) has been designed to effectively reach the ?target?blood glucose and HbA1c levels associated with the lowest mortality rate.The most popular scheme is combined treatment with metformin andsulfonylureasthatmakes possible the achievement of the ?target? metabolic indices in the majority of DM2 patients. However, specific cardiovascular efficiency ofthis therapy is a matter of controversy. The safest modalities of combined therapy are discussed based on the analysis of relevant epidemiological data.Andrey Alexeevich AleksandrovSvetlana Semenovna KukharenkoMaria Nikolaevna YadrikhinskayaEndocrinology Research Centrearticletype 2 diabetes mellitusalgorithm of hypoglycemic therapycardiovascular complicationsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 4, Pp 30-37 (2010)
institution DOAJ
collection DOAJ
language EN
RU
topic type 2 diabetes mellitus
algorithm of hypoglycemic therapy
cardiovascular complications
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle type 2 diabetes mellitus
algorithm of hypoglycemic therapy
cardiovascular complications
Nutritional diseases. Deficiency diseases
RC620-627
Andrey Alexeevich Aleksandrov
Svetlana Semenovna Kukharenko
Maria Nikolaevna Yadrikhinskaya
Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
description The modern algorithm of hypoglycemic therapy for patients with type 2 diabetes mellitus (DM2) has been designed to effectively reach the ?target?blood glucose and HbA1c levels associated with the lowest mortality rate.The most popular scheme is combined treatment with metformin andsulfonylureasthatmakes possible the achievement of the ?target? metabolic indices in the majority of DM2 patients. However, specific cardiovascular efficiency ofthis therapy is a matter of controversy. The safest modalities of combined therapy are discussed based on the analysis of relevant epidemiological data.
format article
author Andrey Alexeevich Aleksandrov
Svetlana Semenovna Kukharenko
Maria Nikolaevna Yadrikhinskaya
author_facet Andrey Alexeevich Aleksandrov
Svetlana Semenovna Kukharenko
Maria Nikolaevna Yadrikhinskaya
author_sort Andrey Alexeevich Aleksandrov
title Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
title_short Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
title_full Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
title_fullStr Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
title_full_unstemmed Cardiovascular implications of modern algorithm of hypoglycemic therapy: ?Florentine hypothesis?
title_sort cardiovascular implications of modern algorithm of hypoglycemic therapy: ?florentine hypothesis?
publisher Endocrinology Research Centre
publishDate 2010
url https://doaj.org/article/0ef17485173f4d6dba361fd590ee9427
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AT marianikolaevnayadrikhinskaya cardiovascularimplicationsofmodernalgorithmofhypoglycemictherapyflorentinehypothesis
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