Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases

Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentor...

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Autores principales:	Brent Berry, Stephanie Joppa, Edward Labin, Vikram Puram, Kaci McCleary, H. Brent Clark, Flavia Nelson
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	CLIPPERS brainstem perivascular infiltration neuroinflammation autoimmune disease Science Q
Acceso en línea:	https://doaj.org/article/0ef4edbbd52145b6aa1f53a3102a268b
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spelling	oai:doaj.org-article:0ef4edbbd52145b6aa1f53a3102a268b2021-11-25T18:10:26ZChronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases10.3390/life111111202075-1729https://doaj.org/article/0ef4edbbd52145b6aa1f53a3102a268b2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-1729/11/11/1120https://doaj.org/toc/2075-1729Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentorial involvement with symmetric and non-confluent lesions in the medial orbitofrontal cortex; additionally, this is the second case to describe an association between diagnoses of hypothyroidism and CLIPPERS.Brent BerryStephanie JoppaEdward LabinVikram PuramKaci McClearyH. Brent ClarkFlavia NelsonMDPI AGarticleCLIPPERSbrainstemperivascular infiltrationneuroinflammationautoimmune diseaseScienceQENLife, Vol 11, Iss 1120, p 1120 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	CLIPPERS brainstem perivascular infiltration neuroinflammation autoimmune disease Science Q
spellingShingle	CLIPPERS brainstem perivascular infiltration neuroinflammation autoimmune disease Science Q Brent Berry Stephanie Joppa Edward Labin Vikram Puram Kaci McCleary H. Brent Clark Flavia Nelson Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
description	Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentorial involvement with symmetric and non-confluent lesions in the medial orbitofrontal cortex; additionally, this is the second case to describe an association between diagnoses of hypothyroidism and CLIPPERS.
format	article
author	Brent Berry Stephanie Joppa Edward Labin Vikram Puram Kaci McCleary H. Brent Clark Flavia Nelson
author_facet	Brent Berry Stephanie Joppa Edward Labin Vikram Puram Kaci McCleary H. Brent Clark Flavia Nelson
author_sort	Brent Berry
title	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_short	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_full	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_fullStr	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_full_unstemmed	Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_sort	chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids may extend above and below pons and is associated with other autoimmune diseases
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/0ef4edbbd52145b6aa1f53a3102a268b
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Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases

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