Target Abundance-Based Fitness Screening (TAFiS) Facilitates Rapid Identification of Target-Specific and Physiologically Active Chemical Probes

ABSTRACT Traditional approaches to drug discovery are frustratingly inefficient and have several key limitations that severely constrain our capacity to rapidly identify and develop novel experimental therapeutics. To address this, we have devised a second-generation target-based whole-cell screenin...

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Autores principales: Arielle Butts, Christian DeJarnette, Tracy L. Peters, Josie E. Parker, Morgan E. Kerns, Karen E. Eberle, Steve L. Kelly, Glen E. Palmer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/0ef5acc8ba6b48e0acfad3d99008315a
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