Effect of pullulan nanoparticle surface charges on HSA complexation and drug release behavior of HSA-bound nanoparticles.

Nanoparticle (NP) compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA) binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs). Here, we pre...

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Autores principales: Xiaojun Tao, Qiufang Zhang, Kai Ling, Yicun Chen, Wenzhi Yang, Fenfei Gao, Ganggang Shi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/0ef9805db5e04b3fb74aadb5c666914f
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