EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.

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Autores principales: Lingling Jiang, Yingying Shen, Danfeng Guo, Diya Yang, Jiajun Liu, Xuefeng Fei, Yunshan Yang, Buyi Zhang, Zhendong Lin, Fei Yang, Xiaojian Wang, Keyi Wang, Jianli Wang, Zhijian Cai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c
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spelling oai:doaj.org-article:0f001c45d44d4449bc6667aedb702e5c2021-12-02T17:32:37ZEpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance10.1038/ncomms130452041-1723https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13045https://doaj.org/toc/2041-1723The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.Lingling JiangYingying ShenDanfeng GuoDiya YangJiajun LiuXuefeng FeiYunshan YangBuyi ZhangZhendong LinFei YangXiaojian WangKeyi WangJianli WangZhijian CaiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lingling Jiang
Yingying Shen
Danfeng Guo
Diya Yang
Jiajun Liu
Xuefeng Fei
Yunshan Yang
Buyi Zhang
Zhendong Lin
Fei Yang
Xiaojian Wang
Keyi Wang
Jianli Wang
Zhijian Cai
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
description The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.
format article
author Lingling Jiang
Yingying Shen
Danfeng Guo
Diya Yang
Jiajun Liu
Xuefeng Fei
Yunshan Yang
Buyi Zhang
Zhendong Lin
Fei Yang
Xiaojian Wang
Keyi Wang
Jianli Wang
Zhijian Cai
author_facet Lingling Jiang
Yingying Shen
Danfeng Guo
Diya Yang
Jiajun Liu
Xuefeng Fei
Yunshan Yang
Buyi Zhang
Zhendong Lin
Fei Yang
Xiaojian Wang
Keyi Wang
Jianli Wang
Zhijian Cai
author_sort Lingling Jiang
title EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
title_short EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
title_full EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
title_fullStr EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
title_full_unstemmed EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
title_sort epcam-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c
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