EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.
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Nature Portfolio
2016
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Acceso en línea: | https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c |
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oai:doaj.org-article:0f001c45d44d4449bc6667aedb702e5c2021-12-02T17:32:37ZEpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance10.1038/ncomms130452041-1723https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13045https://doaj.org/toc/2041-1723The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.Lingling JiangYingying ShenDanfeng GuoDiya YangJiajun LiuXuefeng FeiYunshan YangBuyi ZhangZhendong LinFei YangXiaojian WangKeyi WangJianli WangZhijian CaiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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Science Q Lingling Jiang Yingying Shen Danfeng Guo Diya Yang Jiajun Liu Xuefeng Fei Yunshan Yang Buyi Zhang Zhendong Lin Fei Yang Xiaojian Wang Keyi Wang Jianli Wang Zhijian Cai EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
description |
The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells. |
format |
article |
author |
Lingling Jiang Yingying Shen Danfeng Guo Diya Yang Jiajun Liu Xuefeng Fei Yunshan Yang Buyi Zhang Zhendong Lin Fei Yang Xiaojian Wang Keyi Wang Jianli Wang Zhijian Cai |
author_facet |
Lingling Jiang Yingying Shen Danfeng Guo Diya Yang Jiajun Liu Xuefeng Fei Yunshan Yang Buyi Zhang Zhendong Lin Fei Yang Xiaojian Wang Keyi Wang Jianli Wang Zhijian Cai |
author_sort |
Lingling Jiang |
title |
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
title_short |
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
title_full |
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
title_fullStr |
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
title_full_unstemmed |
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
title_sort |
epcam-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/0f001c45d44d4449bc6667aedb702e5c |
work_keys_str_mv |
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