Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress

Abstract Autophagy is a highly conserved process of degradation of cytoplasmic constituents in eukaryotes. It is involved in the growth and development of plants, as well as in biotic and abiotic stress response. Although autophagy-related (ATG) genes have been identified and characterized in many p...

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Autores principales:	Mingkang Yang, Liping Wang, Chumin Chen, Xu Guo, Chuanglie Lin, Wei Huang, Liang Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/0f012d232cdb4078ad8f618099c49ac0
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spelling	oai:doaj.org-article:0f012d232cdb4078ad8f618099c49ac02021-11-28T12:17:25ZGenome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress10.1038/s41598-021-02239-62045-2322https://doaj.org/article/0f012d232cdb4078ad8f618099c49ac02021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02239-6https://doaj.org/toc/2045-2322Abstract Autophagy is a highly conserved process of degradation of cytoplasmic constituents in eukaryotes. It is involved in the growth and development of plants, as well as in biotic and abiotic stress response. Although autophagy-related (ATG) genes have been identified and characterized in many plant species, little is known about this process in Medicago truncatula. In this study, 39 ATGs were identified, and their gene structures and conserved domains were systematically characterized in M. truncatula. Many cis-elements, related to hormone and stress responsiveness, were identified in the promoters of MtATGs. Phylogenetic and interaction network analyses suggested that the function of MtATGs is evolutionarily conserved in Arabidopsis and M. truncatula. The expression of MtATGs, at varied levels, was detected in all examined tissues. In addition, most of the MtATGs were highly induced during seed development and drought stress, which indicates that autophagy plays an important role in seed development and responses to drought stress in M. truncatula. In conclusion, this study gives a comprehensive overview of MtATGs and provides important clues for further functional analysis of autophagy in M. truncatula.Mingkang YangLiping WangChumin ChenXu GuoChuanglie LinWei HuangLiang ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mingkang Yang Liping Wang Chumin Chen Xu Guo Chuanglie Lin Wei Huang Liang Chen Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
description	Abstract Autophagy is a highly conserved process of degradation of cytoplasmic constituents in eukaryotes. It is involved in the growth and development of plants, as well as in biotic and abiotic stress response. Although autophagy-related (ATG) genes have been identified and characterized in many plant species, little is known about this process in Medicago truncatula. In this study, 39 ATGs were identified, and their gene structures and conserved domains were systematically characterized in M. truncatula. Many cis-elements, related to hormone and stress responsiveness, were identified in the promoters of MtATGs. Phylogenetic and interaction network analyses suggested that the function of MtATGs is evolutionarily conserved in Arabidopsis and M. truncatula. The expression of MtATGs, at varied levels, was detected in all examined tissues. In addition, most of the MtATGs were highly induced during seed development and drought stress, which indicates that autophagy plays an important role in seed development and responses to drought stress in M. truncatula. In conclusion, this study gives a comprehensive overview of MtATGs and provides important clues for further functional analysis of autophagy in M. truncatula.
format	article
author	Mingkang Yang Liping Wang Chumin Chen Xu Guo Chuanglie Lin Wei Huang Liang Chen
author_facet	Mingkang Yang Liping Wang Chumin Chen Xu Guo Chuanglie Lin Wei Huang Liang Chen
author_sort	Mingkang Yang
title	Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
title_short	Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
title_full	Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
title_fullStr	Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
title_full_unstemmed	Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress
title_sort	genome-wide analysis of autophagy-related genes in medicago truncatula highlights their roles in seed development and response to drought stress
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/0f012d232cdb4078ad8f618099c49ac0
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Genome-wide analysis of autophagy-related genes in Medicago truncatula highlights their roles in seed development and response to drought stress

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