Spatial constraints govern competition of mutant clones in human epidermis

Deep sequencing technologies allow for the investigation of clonal evolution in human cancers. Here the authors, combining sequencing data from human skin with mathematical modelling and simulations, suggest that the spatial context of a mutation with respect to other mutant clones may lead to diffe...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: M. D. Lynch, C. N. S. Lynch, E. Craythorne, K. Liakath-Ali, R. Mallipeddi, J. N. Barker, F. M. Watt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/0f0d3a09923e4b6eb97e3107824208bf
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares