A biochemical network controlling basal myosin oscillation

The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of...

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Autores principales: Xiang Qin, Edouard Hannezo, Thomas Mangeat, Chang Liu, Pralay Majumder, Jiaying Liu, Valerie Choesmel-Cadamuro, Jocelyn A. McDonald, Yiyao Liu, Bin Yi, Xiaobo Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e31
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spelling oai:doaj.org-article:0f0e9448479a40fa8dc968a66bdc2e312021-12-02T16:57:00ZA biochemical network controlling basal myosin oscillation10.1038/s41467-018-03574-52041-1723https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e312018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03574-5https://doaj.org/toc/2041-1723The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of myosin phosphatase that shuts off the signal.Xiang QinEdouard HannezoThomas MangeatChang LiuPralay MajumderJiaying LiuValerie Choesmel-CadamuroJocelyn A. McDonaldYiyao LiuBin YiXiaobo WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiang Qin
Edouard Hannezo
Thomas Mangeat
Chang Liu
Pralay Majumder
Jiaying Liu
Valerie Choesmel-Cadamuro
Jocelyn A. McDonald
Yiyao Liu
Bin Yi
Xiaobo Wang
A biochemical network controlling basal myosin oscillation
description The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of myosin phosphatase that shuts off the signal.
format article
author Xiang Qin
Edouard Hannezo
Thomas Mangeat
Chang Liu
Pralay Majumder
Jiaying Liu
Valerie Choesmel-Cadamuro
Jocelyn A. McDonald
Yiyao Liu
Bin Yi
Xiaobo Wang
author_facet Xiang Qin
Edouard Hannezo
Thomas Mangeat
Chang Liu
Pralay Majumder
Jiaying Liu
Valerie Choesmel-Cadamuro
Jocelyn A. McDonald
Yiyao Liu
Bin Yi
Xiaobo Wang
author_sort Xiang Qin
title A biochemical network controlling basal myosin oscillation
title_short A biochemical network controlling basal myosin oscillation
title_full A biochemical network controlling basal myosin oscillation
title_fullStr A biochemical network controlling basal myosin oscillation
title_full_unstemmed A biochemical network controlling basal myosin oscillation
title_sort biochemical network controlling basal myosin oscillation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e31
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