A biochemical network controlling basal myosin oscillation
The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of...
Guardado en:
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e31 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:0f0e9448479a40fa8dc968a66bdc2e31 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:0f0e9448479a40fa8dc968a66bdc2e312021-12-02T16:57:00ZA biochemical network controlling basal myosin oscillation10.1038/s41467-018-03574-52041-1723https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e312018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03574-5https://doaj.org/toc/2041-1723The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of myosin phosphatase that shuts off the signal.Xiang QinEdouard HannezoThomas MangeatChang LiuPralay MajumderJiaying LiuValerie Choesmel-CadamuroJocelyn A. McDonaldYiyao LiuBin YiXiaobo WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Xiang Qin Edouard Hannezo Thomas Mangeat Chang Liu Pralay Majumder Jiaying Liu Valerie Choesmel-Cadamuro Jocelyn A. McDonald Yiyao Liu Bin Yi Xiaobo Wang A biochemical network controlling basal myosin oscillation |
description |
The actomyosin cytoskeleton is known to spontaneously oscillate in many systems but the mechanism of this behavior is not clear. Here Qin et al. define a signaling network involving a ROCK-dependent self-activation loop and recruitment of myosin II to the cortex, followed by a local accumulation of myosin phosphatase that shuts off the signal. |
format |
article |
author |
Xiang Qin Edouard Hannezo Thomas Mangeat Chang Liu Pralay Majumder Jiaying Liu Valerie Choesmel-Cadamuro Jocelyn A. McDonald Yiyao Liu Bin Yi Xiaobo Wang |
author_facet |
Xiang Qin Edouard Hannezo Thomas Mangeat Chang Liu Pralay Majumder Jiaying Liu Valerie Choesmel-Cadamuro Jocelyn A. McDonald Yiyao Liu Bin Yi Xiaobo Wang |
author_sort |
Xiang Qin |
title |
A biochemical network controlling basal myosin oscillation |
title_short |
A biochemical network controlling basal myosin oscillation |
title_full |
A biochemical network controlling basal myosin oscillation |
title_fullStr |
A biochemical network controlling basal myosin oscillation |
title_full_unstemmed |
A biochemical network controlling basal myosin oscillation |
title_sort |
biochemical network controlling basal myosin oscillation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/0f0e9448479a40fa8dc968a66bdc2e31 |
work_keys_str_mv |
AT xiangqin abiochemicalnetworkcontrollingbasalmyosinoscillation AT edouardhannezo abiochemicalnetworkcontrollingbasalmyosinoscillation AT thomasmangeat abiochemicalnetworkcontrollingbasalmyosinoscillation AT changliu abiochemicalnetworkcontrollingbasalmyosinoscillation AT pralaymajumder abiochemicalnetworkcontrollingbasalmyosinoscillation AT jiayingliu abiochemicalnetworkcontrollingbasalmyosinoscillation AT valeriechoesmelcadamuro abiochemicalnetworkcontrollingbasalmyosinoscillation AT jocelynamcdonald abiochemicalnetworkcontrollingbasalmyosinoscillation AT yiyaoliu abiochemicalnetworkcontrollingbasalmyosinoscillation AT binyi abiochemicalnetworkcontrollingbasalmyosinoscillation AT xiaobowang abiochemicalnetworkcontrollingbasalmyosinoscillation AT xiangqin biochemicalnetworkcontrollingbasalmyosinoscillation AT edouardhannezo biochemicalnetworkcontrollingbasalmyosinoscillation AT thomasmangeat biochemicalnetworkcontrollingbasalmyosinoscillation AT changliu biochemicalnetworkcontrollingbasalmyosinoscillation AT pralaymajumder biochemicalnetworkcontrollingbasalmyosinoscillation AT jiayingliu biochemicalnetworkcontrollingbasalmyosinoscillation AT valeriechoesmelcadamuro biochemicalnetworkcontrollingbasalmyosinoscillation AT jocelynamcdonald biochemicalnetworkcontrollingbasalmyosinoscillation AT yiyaoliu biochemicalnetworkcontrollingbasalmyosinoscillation AT binyi biochemicalnetworkcontrollingbasalmyosinoscillation AT xiaobowang biochemicalnetworkcontrollingbasalmyosinoscillation |
_version_ |
1718382605528727552 |