Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators

An emerging neurostimulation therapy utilizes electroceuticals to treat numerous neurological disorders. With the aim to discover novel clinical applications of neural stimulation, device miniaturization has been a key challenge for successful clinical translation of implantable stimulators. The bat...

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Autores principales:	Kyungmin Kim, Seok Geun Jang, Hae Gyun Lim, Hyung Ham Kim, Sung-Min Park
Formato:	article
Lenguaje:	EN
Publicado:	IEEE 2021
Materias:	Neurostimulator miniaturization implantable device acoustic power transfer nerve stimulation Electrical engineering. Electronics. Nuclear engineering TK1-9971
Acceso en línea:	https://doaj.org/article/0f1034f751b74c0b90a62e28e84e3ba0
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id	oai:doaj.org-article:0f1034f751b74c0b90a62e28e84e3ba0
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spelling	oai:doaj.org-article:0f1034f751b74c0b90a62e28e84e3ba02021-11-24T00:03:15ZAcoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators2169-353610.1109/ACCESS.2021.3127875https://doaj.org/article/0f1034f751b74c0b90a62e28e84e3ba02021-01-01T00:00:00Zhttps://ieeexplore.ieee.org/document/9614139/https://doaj.org/toc/2169-3536An emerging neurostimulation therapy utilizes electroceuticals to treat numerous neurological disorders. With the aim to discover novel clinical applications of neural stimulation, device miniaturization has been a key challenge for successful clinical translation of implantable stimulators. The battery size has been a limiting factor in further miniaturization, so wireless power transfer without the use of an implanted battery has gained interest. Among various power transfer techniques, acoustic power transfer (APT) provides substantial benefits for powering implantable devices due to its proven safety and efficiency for human body penetration. In this study, we proposed an APT-based neurostimulator with an integrated self-focused 3.6 MHz acoustic transducer and a receiver circuit composed of a power management module and pulse generator. The size of the entire device was 8 mm <inline-formula> <tex-math notation="LaTeX">$\times$ </tex-math></inline-formula> 8 mm <inline-formula> <tex-math notation="LaTeX">$\times8.6$ </tex-math></inline-formula> mm, which is small enough to be implanted with a small incision. A focused beam generated by an external transmitter was received by another focused beam from a receiver transducer, and this optimized pair of transducers with a receiver circuit generated 1.5 V, 1.3 ms pulse trains, which successfully transmitted stimulation pulses. We adopted a 1–3 composite with a piezolayer to implement a curved aperture, which enabled less-attenuated, focused, and matched beams for maximization of power transfer efficiency. We evaluated APT performance through rigorous bench-top and phantom tests and demonstrated the feasibility of stimulation through an <italic>in vivo</italic> experiment of sciatic nerve stimulation using a rat model.Kyungmin KimSeok Geun JangHae Gyun LimHyung Ham KimSung-Min ParkIEEEarticleNeurostimulatorminiaturizationimplantable deviceacoustic power transfernerve stimulationElectrical engineering. Electronics. Nuclear engineeringTK1-9971ENIEEE Access, Vol 9, Pp 153850-153862 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurostimulator miniaturization implantable device acoustic power transfer nerve stimulation Electrical engineering. Electronics. Nuclear engineering TK1-9971
spellingShingle	Neurostimulator miniaturization implantable device acoustic power transfer nerve stimulation Electrical engineering. Electronics. Nuclear engineering TK1-9971 Kyungmin Kim Seok Geun Jang Hae Gyun Lim Hyung Ham Kim Sung-Min Park Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
description	An emerging neurostimulation therapy utilizes electroceuticals to treat numerous neurological disorders. With the aim to discover novel clinical applications of neural stimulation, device miniaturization has been a key challenge for successful clinical translation of implantable stimulators. The battery size has been a limiting factor in further miniaturization, so wireless power transfer without the use of an implanted battery has gained interest. Among various power transfer techniques, acoustic power transfer (APT) provides substantial benefits for powering implantable devices due to its proven safety and efficiency for human body penetration. In this study, we proposed an APT-based neurostimulator with an integrated self-focused 3.6 MHz acoustic transducer and a receiver circuit composed of a power management module and pulse generator. The size of the entire device was 8 mm <inline-formula> <tex-math notation="LaTeX">$\times$ </tex-math></inline-formula> 8 mm <inline-formula> <tex-math notation="LaTeX">$\times8.6$ </tex-math></inline-formula> mm, which is small enough to be implanted with a small incision. A focused beam generated by an external transmitter was received by another focused beam from a receiver transducer, and this optimized pair of transducers with a receiver circuit generated 1.5 V, 1.3 ms pulse trains, which successfully transmitted stimulation pulses. We adopted a 1–3 composite with a piezolayer to implement a curved aperture, which enabled less-attenuated, focused, and matched beams for maximization of power transfer efficiency. We evaluated APT performance through rigorous bench-top and phantom tests and demonstrated the feasibility of stimulation through an <italic>in vivo</italic> experiment of sciatic nerve stimulation using a rat model.
format	article
author	Kyungmin Kim Seok Geun Jang Hae Gyun Lim Hyung Ham Kim Sung-Min Park
author_facet	Kyungmin Kim Seok Geun Jang Hae Gyun Lim Hyung Ham Kim Sung-Min Park
author_sort	Kyungmin Kim
title	Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
title_short	Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
title_full	Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
title_fullStr	Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
title_full_unstemmed	Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators
title_sort	acoustic power transfer using self-focused transducers for miniaturized implantable neurostimulators
publisher	IEEE
publishDate	2021
url	https://doaj.org/article/0f1034f751b74c0b90a62e28e84e3ba0
work_keys_str_mv	AT kyungminkim acousticpowertransferusingselffocusedtransducersforminiaturizedimplantableneurostimulators AT seokgeunjang acousticpowertransferusingselffocusedtransducersforminiaturizedimplantableneurostimulators AT haegyunlim acousticpowertransferusingselffocusedtransducersforminiaturizedimplantableneurostimulators AT hyunghamkim acousticpowertransferusingselffocusedtransducersforminiaturizedimplantableneurostimulators AT sungminpark acousticpowertransferusingselffocusedtransducersforminiaturizedimplantableneurostimulators
_version_	1718416077455622144

Acoustic Power Transfer Using Self-Focused Transducers for Miniaturized Implantable Neurostimulators

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