Diagnosis of prostate cancer via nanotechnological approach
Benedict J Kang,1,2,* Minhong Jeun,1,2,* Gun Hyuk Jang,1,2 Sang Hoon Song,3 In Gab Jeong,3 Choung-Soo Kim,3 Peter C Searson,4 Kwan Hyi Lee1,2 1KIST Biomedical Research Institute, 2Department of Biomedical Engineering, Korea University of Science and Technology (UST), 3Department of Urology, Asan Med...
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Dove Medical Press
2015
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oai:doaj.org-article:0f1c5e9c53244c68a8c8d5d8901f30e22021-12-02T08:10:51ZDiagnosis of prostate cancer via nanotechnological approach1178-2013https://doaj.org/article/0f1c5e9c53244c68a8c8d5d8901f30e22015-10-01T00:00:00Zhttps://www.dovepress.com/diagnosis-of-prostate-cancer-via-nanotechnological-approach-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Benedict J Kang,1,2,* Minhong Jeun,1,2,* Gun Hyuk Jang,1,2 Sang Hoon Song,3 In Gab Jeong,3 Choung-Soo Kim,3 Peter C Searson,4 Kwan Hyi Lee1,2 1KIST Biomedical Research Institute, 2Department of Biomedical Engineering, Korea University of Science and Technology (UST), 3Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 4Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA *These authors contributed equally to this work Abstract: Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.Keywords: bioassay, nanomaterial, nanodevice, PSA, non-PSA biomarker, bodily fluidKang BJJeun MJang GHSong SHJeong IGKim CSSearson PCLee KHDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 6555-6569 (2015) |
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Medicine (General) R5-920 Kang BJ Jeun M Jang GH Song SH Jeong IG Kim CS Searson PC Lee KH Diagnosis of prostate cancer via nanotechnological approach |
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Benedict J Kang,1,2,* Minhong Jeun,1,2,* Gun Hyuk Jang,1,2 Sang Hoon Song,3 In Gab Jeong,3 Choung-Soo Kim,3 Peter C Searson,4 Kwan Hyi Lee1,2 1KIST Biomedical Research Institute, 2Department of Biomedical Engineering, Korea University of Science and Technology (UST), 3Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 4Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA *These authors contributed equally to this work Abstract: Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.Keywords: bioassay, nanomaterial, nanodevice, PSA, non-PSA biomarker, bodily fluid |
format |
article |
author |
Kang BJ Jeun M Jang GH Song SH Jeong IG Kim CS Searson PC Lee KH |
author_facet |
Kang BJ Jeun M Jang GH Song SH Jeong IG Kim CS Searson PC Lee KH |
author_sort |
Kang BJ |
title |
Diagnosis of prostate cancer via nanotechnological approach |
title_short |
Diagnosis of prostate cancer via nanotechnological approach |
title_full |
Diagnosis of prostate cancer via nanotechnological approach |
title_fullStr |
Diagnosis of prostate cancer via nanotechnological approach |
title_full_unstemmed |
Diagnosis of prostate cancer via nanotechnological approach |
title_sort |
diagnosis of prostate cancer via nanotechnological approach |
publisher |
Dove Medical Press |
publishDate |
2015 |
url |
https://doaj.org/article/0f1c5e9c53244c68a8c8d5d8901f30e2 |
work_keys_str_mv |
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1718398584918900736 |