RNA Activation—A Novel Approach to Therapeutically Upregulate Gene Transcription
RNA activation (RNAa) is a mechanism whereby RNA oligos complementary to genomic sequences around the promoter region of genes increase the transcription output of their target gene. Small activating RNA (saRNA) mediate RNAa through interaction with protein co-factors to facilitate RNA polymerase II...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/0f1f50fad12e4368b4b26d264f7522fe |
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